23422-53-9 Usage
Description
Formetanate hydrochloride is a white or yellowish crystalline solid or powder with a faint odor. It is used as a plant insecticide, acaricide, and miticide, and is known for its contact and stomach action.
Uses
Used in Agricultural Industry:
Formetanate hydrochloride is used as an insecticide and acaricide for controlling spider mites and some insects (Diptera, Hemiptera, and Thysanoptera) on ornamentals, fruit, vegetables, and alfalfa. It is registered for use in the U.S. but not listed for use in EU countries.
Used in Fruit Crop Protection:
Formetanate hydrochloride is used as an insecticide for thrips and true bug control on fruit crops, providing effective protection against these pests and helping to maintain the quality and yield of the crops.
Air & Water Reactions
Hydrolyzed at pH less than 4 [EPA, 1998].
Reactivity Profile
FORMETANATE HYDROCHLORIDE is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.
Health Hazard
Extremely toxic to humans. Not absorbed through contact with skin. Inhalation or ingestion may cause poisoning. Inhibits cholinesterase activity so effects are in relation to action on nervous system and can result in death.
Fire Hazard
FORMETANATE HYDROCHLORIDE may burn but does not ignite readily. Container may explode in heat of fire. Hydrolyzed at pH less than 4
Trade name
CARZOL?; CARZOL? SP;
DICARZOL?; ENT 27566?; EP-332?; MORTON?
EP332; NOR-AM? EP 332; SCHERING? 36056; SN
36056?
Safety Profile
Poison by ingestion and
intraperitoneal routes. Mddly toxic by skin
contact. When heated to decomposition it
emits very toxic fumes of NOx and HCl.
Potential Exposure
A potential danger to those involved
in the manufacture, formulation, and application of this
plant insecticide, acaricide and miticide.
Metabolic pathway
Formetanate is hydrolysed rapidly in field and laboratory soils under
aerobic and anaerobic conditions. It is metabolised by similar pathways in
plants and animals. It is hydrolytically deaminated to produce a formyl
derivative and subsequently hydrolysed at the carbamate ester to give a
phenolic product. The phenol is deformylated to 3-aminophenol and
acetylated to 3-acetamidophenol. Formetanate and most phase 1 metabolites
are found conjugated. Its metabolism has been reviewed by Cool
and Jankowski (1985), Fukuto (1972) and Kuhr and Dorough (1976).
Shipping
UN2757 Carbamate pesticides, solid, toxic,
Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1;
Labels: 6.1-Poisonous materials, Technical Name Required.
Degradation
Formetanate is hydrolysed rapidly under basic conditions. DT50 values at
pH 5, 7 and 9 (22 °C) are reported to be 65 days, 23 hours and 2 hours,
respectively (PM). The photolysis of formetanate hydrochloride in solutions
of distilled water at pH 3.1 and 7.1 or natural river water was
studied. Samples were irradiated for 4 days by a high pressure Hg
lamp immersed in the solutions. Light of wavelength <286 nm was filtered
out. Analysis of solutions was by TLC, IR and MS. The carbamate moiety
was more stable than the formamidine. Photolysis gave four products,
viz. the formaminophenol (2), the 3-aminophenyl carbamate (3), the
formamino compound (4) and 3-hydroxyphenyl methylcarbamate (5), a product of oxidative deamination of formetanate. Yields increased in the
order given. The proposed pathways of photolysis of formetanate are
given in Scheme 1 (Su and Zabick, 1972). Soil surface photolysis occurs
with a DT50 value of 16 hours (PM).
Incompatibilities
Carbamates are incompatible with strong
acids and bases, and especially incompatible with strong
reducing agents such as hydrideds and active metals.
Contact with active metals or nitrides form flammable gas eous hydrogen. Incompatible with strongly oxidizing acids,
peroxides, and hydroperoxides.
Waste Disposal
In accordance with 40CFR
165 recommendations for the disposal of pesticides and
pesticide containers. Must be disposed properly by follow ing package label directions or by contacting your local or
federal environmental control agency, or by contacting
your regional EPA office. Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant
(≥kg/mo) must conform with EPA regulations gov erning storage, transportation, treatment, and waste
disposal.
Check Digit Verification of cas no
The CAS Registry Mumber 23422-53-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,4,2 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 23422-53:
(7*2)+(6*3)+(5*4)+(4*2)+(3*2)+(2*5)+(1*3)=79
79 % 10 = 9
So 23422-53-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H/b13-8-;
