23244-46-4

Basic information

• Product Name: 5(4H)-Isoxazolone, 4-[(4-methylphenyl)methylene]-3-phenyl-
• CAS NO: 23244-46-4
• Molecular Formula: C17H13NO2
• Molecular Weight: 263.296
• Mol File: 23244-46-4.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 5(4H)-Isoxazolone, 4-[(4-methylphenyl)methylene]-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5(4H)-Isoxazolone, 4-[(4-methylphenyl)methylene]-3-phenyl-(23244-46-4)
• EPA Substance Registry System: 5(4H)-Isoxazolone, 4-[(4-methylphenyl)methylene]-3-phenyl-(23244-46-4)

Safety Data

• Hazardous Substances Data: 23244-46-4(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 1076-59-1 3-phenyl-4H-isoxazol-5-one 
• 1227841-04-4 (E)-benzaldehyde O-3-phenylpropioloyl oxime 
• 1227841-25-9 (E)-4-isopropylbenzaldehyde O-3-(4-methylphenyl)propioloyl oxime 
• 1227841-23-7 (E)-4-methylbenzaldehyde O-3-(4-methylphenyl)propioloyl oxime 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 127916-11-4 ethyl bezoylacetate oxime 
• 7713-79-3 3-phenyl-5-isoxazolone 

Downstream Products

• 50780-01-3 meso-1,7,1',7'-hexaphenyl-2c,2'c'-di-p-tolyl-(1ξH,3rC⁴,1'ξH,3'r'C^4')-[1,1']bi[5-oxa-6-aza-spiro[2.4]heptyl]-6,6'-diene-4,4'-dione 
• 335373-27-8 C₃₀H₂₄N₂O₃ 
• 1206892-33-2 N-tert-butyl-2-(5-oxo-3-phenyl-4,5-dihydro-isoxazol-4-yl)-2-p-tolyl-acetamide 
• 1206892-68-3 2-(2-(5-oxo-3-phenyl-2,5-dihydroisoxazol-4-yl)-2-p-tolylacetamido)acetic acid ethyl ester 
• 1206892-69-4 N-benzyl-2-(5-oxo-3-phenyl-2,5-dihydro-isoxazol-4-yl)-2-p-tolyl-acetamide 
• 7118-66-3 5-methyl-2-(4-methylphenyl)-1H-benzimidazole 
• 89114-10-3 4-(4-Methyl-benzyl)-3-phenyl-2H-isoxazol-5-one 

Relevant articles and documents

Enantioselective Synthesis of Functionalized Diazaspirocycles from 4-Benzylideneisoxazol-5(4H)-one Derivatives and Isocyanoacetate Esters

Enantioenriched spirocyclic compounds bearing three contiguous stereocenters and high functionalization were obtained through a formal [3+2] cycloaddition reaction catalyzed by a cooperative system. The spiro compounds were synthesized from 4-arylideneisoxazol-5-ones and isocyanoacetate esters using a bifunctional squaramide/Br?nsted base organocatalyst derived from a Cinchona alkaloid and silver oxide as Lewis acid. This method afforded two out of the four possible diastereomers with good yields and high enantiomeric excess for both diastereomers. (Figure presented.).

One-pot green synthesis of isoxazol-5(4H)-one derivatives using Dowex1-x8OH in water

4-(Arylmethylidene)-3-methylisoxazol-5(4H)-ones and 4-(arylmethylidene)-3-phenylisoxazol-5(4H)-ones were synthesized in a one-pot three-component procedure in the presence of Dowex1-x8OH as catalyst in water. The products were obtained in high yields (90-

An easy protocol for the domino synthesis of diversely functionalized spirocarbocycles and their biological evaluation

A base-catalysed domino reaction for the synthesis of spirocarbocycles in excellent yields using chalcones and vinyl malononitriles is reported. This consists of a series of steps including Knoevenagel condensation followed by intermolecular vinylogous Mi