23165-64-2

Basic information

• Product Name: 2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE
• Synonyms: 2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE, 9;2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE
• CAS NO: 23165-64-2
• Molecular Formula: C₇H₃ClN₂O₂S
• Molecular Weight: 214.63
• EINECS: -0
• Product Categories: Organic Building Blocks;Sulfur Compounds;Thiocyanates/Isothiocyanates
• Mol File: 23165-64-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 95-99 °C(lit.)
• Boiling Point: 354.1 °C at 760 mmHg
• Flash Point: 167.9 °C
• Appearance: /
• Density: 1.48g/cm³
• Vapor Pressure: 7.01E-05mmHg at 25°C
• Refractive Index: 1.651
• Sensitive: Moisture Sensitive
• BRN: 2972987
• CAS DataBase Reference: 2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE(23165-64-2)
• EPA Substance Registry System: 2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE(23165-64-2)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: 2811
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 23165-64-2(Hazardous Substances Data)

Usage

Description

2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE, also known as 2-Chloro-1-isothiocyanato-4-nitrobenzene, is an organic compound that serves as a versatile intermediate in the synthesis of various chemical compounds. It is characterized by its isothiocyanate and nitro functional groups, which contribute to its reactivity and potential applications in different industries.

Uses

Used in Pharmaceutical Industry:
2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE is used as a synthetic intermediate for the development of substituted thiocarboxamides, carboxamides, and thioureas. These synthesized compounds exhibit potential anthelmintic and antimicrobial properties, making them valuable in the treatment of parasitic infections and combating microbial growth.
Used in Chemical Synthesis:
In the chemical industry, 2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE is utilized as a key building block for the synthesis of a wide range of chemical products. Its unique structure allows for various chemical reactions, leading to the creation of new compounds with diverse applications in different fields.
Used in Research and Development:
Due to its reactivity and potential for creating novel compounds, 2-CHLORO-4-NITROPHENYL ISOTHIOCYANATE is also employed in research and development laboratories. Scientists and researchers use this compound to explore new chemical reactions, develop innovative products, and study its properties for potential applications in various industries.

InChI:InChI=1/C7H3ClN2O2S/c8-6-3-5(10(11)12)1-2-7(6)9-4-13/h1-3H

Upstream product

• 463-71-8 thiophosgene 
• 121-87-9 2-Chloro-4-nitroaniline 

Downstream Products

• 78740-21-3 4-Methyl-piperazine-1-carbothioic acid (2-chloro-4-nitro-phenyl)-amide 
• 78721-82-1 1-(1H-Benzoimidazol-2-yl)-3-(2-chloro-4-nitro-phenyl)-thiourea 
• 78721-57-0 4-Phenyl-piperazine-1-carbothioic acid (2-chloro-4-nitro-phenyl)-amide 
• 78993-76-7 N-(2-Chloro-4-nitrophenyl)-N'-<4-(2-hydroxy-5-nitrobenzimidazol-1-yl)phenyl>thiourea 
• 94772-01-7 C₁₈H₁₇ClN₈O₅S 
• 78993-72-3 1-(2-Chloro-4-nitro-phenyl)-3-[4-(5-nitro-benzoimidazol-1-yl)-phenyl]-thiourea 
• 1621608-19-2 N-(2-chloro-4-nitrophenyl)-2-{[4-(tricyclo[3.3.1.1^3,7]dec-1-yl)quinolin-2-yl]carbonyl}hydrazinecarbothioamide 
• 73305-14-3 4-(2-chloro-4-nitrophenyl)-3-thiosemicarbazide 
• 1152594-94-9 O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] 2-chloro-4-nitrophenylthiocarbamate 
• 143014-17-9 4-(2-chloro-4-nitrophenyl)-2-methyl-3-thiosemicarbazide 
• 78721-77-4 4-Benzyl-piperazine-1-carboxylic acid (2-chloro-4-isothiocyanato-phenyl)-amide 
• 78721-78-5 4-Phenyl-piperazine-1-carboxylic acid (2-chloro-4-isothiocyanato-phenyl)-amide 
• 78721-72-9 4-Phenyl-piperazine-1-carbothioic acid (4-amino-2-chloro-phenyl)-amide 
• 78721-71-8 4-Benzyl-piperazine-1-carbothioic acid (4-amino-2-chloro-phenyl)-amide 

Relevant articles and documents

Synthesis of Substituted Thiocarboxamides, Carboxamides and Thioureas as Potential Anthelmintic and Antimicrobial Agents

A series of substituted thiocarboxamides (6-26), carboxamides (27-32), thioureas (33-37) and urea (38) have been synthesized starting from various aryl isothiocyanates (1-5).Their anthelmintic and antimicrobial activities are reported.Of these 8 and 9 show 60-70percent reduction in worms at a dose of 100-250 mg/kg given for three days.