229178-78-3

Basic information

• Product Name: 1-[4-(2-chloro-α,α,α-trifluoro-4-tolyloxy)-2-fluorophenyl]-3-[2,6-difluoro-3-(2-ethoxycarbonylethyl)benzoyl]urea
• CAS NO: 229178-78-3
• Molecular Weight: 588.891
• Mol File: 229178-78-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[4-(2-chloro-α,α,α-trifluoro-4-tolyloxy)-2-fluorophenyl]-3-[2,6-difluoro-3-(2-ethoxycarbonylethyl)benzoyl]urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(2-chloro-α,α,α-trifluoro-4-tolyloxy)-2-fluorophenyl]-3-[2,6-difluoro-3-(2-ethoxycarbonylethyl)benzoyl]urea(229178-78-3)
• EPA Substance Registry System: 1-[4-(2-chloro-α,α,α-trifluoro-4-tolyloxy)-2-fluorophenyl]-3-[2,6-difluoro-3-(2-ethoxycarbonylethyl)benzoyl]urea(229178-78-3)

Safety Data

• Hazardous Substances Data: 229178-78-3(Hazardous Substances Data)

Upstream product

• 101463-63-2 4-(2-chloro-4-(trifluoromethyl)-phenoxy)-2-fluoroaniline 
• 385-00-2 2,6-difluorobenzoic acid 
• 229178-77-2 2,6-difluoro-[2-(ethoxycarbonyl)ethyl]benzamide 
• 229178-76-1 2,6-difluoro-3-[2-(ethoxycarbonyl)vinyl]benzamide 
• 229178-75-0 2,6-difluoro-3-iodobenzamide 
• 229178-74-9 2,6-difluoro-3-iodobenzoic acid 
• 101463-69-8 flufenoxuron 
• 140-88-5 ethyl acrylate 

Downstream Products

• 229178-79-4 1-[4-(2-chloro-α,α,α-trifluoro-4-tolyloxy)-2-fluorophenyl]-3-[2,6-difluoro-3-(2-carbonylethyl)benzoyl]urea 

Relevant articles and documents

Development of a compound-specific ELISA for flufenoxuron and an improved class-specific assay for benzoylphenylurea insect growth regulators

This study describes immunochemical approaches for the compound-specific detection of flufenoxuron and class-specific detection of benzoylphenylurea (BPU) insecticides. With the aim of developing a highly specific immunoassay for flufenoxuron, a hapten was synthesized by introducing a spacer arm at the 2,6-difluoro substituent aromatic ring of a flufenoxuron derivative. An IC50 value of 2.4 ppb was obtained for flufenoxuron, with detection of the other four BPUs being more than 4000-fold less sensitive. For the development of class-specific ELISA for five BPUs, a new approach was used for the hapten preparation in which a butanoic acid linkage was introduced into the 3,5- dichlorosubstitued aniline ring of chlorfluazuron analogue. Although the resultant ELISA still exhibited slightly differing cross-reactions for these five BPUs, this method had broader specificity than the previously reported polyclonal antibody-based ELISA. Spike and recovery studies for five BPUs in soil and water indicated that both the compound- and class-specific ELISAs were able to quantitatively detect BPU residues in soil and water. This study also provided additional insights into the influence of the immunizing hapten structure on the specificities of the antibodies obtained.