22722-98-1 Usage
Description
Sodium bis(2-methoxyethoxy)aluminiumhydride, also known as Red-Al, is a versatile reducing agent in organic synthesis. It is a colorless to light amber liquid with clear to slightly hazy appearance. Its chemical formula is NaAlH2(OCH2CH2OCH3)2.
Uses
Used in Organic Synthesis:
Sodium bis(2-methoxyethoxy)aluminiumhydride is used as a reducing agent for the conversion of various functional groups to primary alcohols and amines. It is used to reduce aldehydes, ketones, carboxylic acids, esters, acyl halides, and anhydrides to primary alcohols. It also reduces ketoximes and aldoximes to primary amines.
Used in the Preparation of Azo Compounds:
Sodium bis(2-methoxyethoxy)aluminiumhydride is used to prepare azoxyarenes, azoarenes, and hydroazoarenes from nitroarenes.
Used in Hydroalumination of Alkenes and Alkynes:
Sodium bis(2-methoxyethoxy)aluminiumhydride is employed in the hydroalumination of alkenes and alkynes.
Used in the Reduction of Lactones and Epoxides:
Sodium bis(2-methoxyethoxy)aluminiumhydride is utilized in the reduction of lactones and epoxides into diols.
Used as a Methylation Reagent:
Sodium bis(2-methoxyethoxy)aluminiumhydride serves as a methylation reagent for aryl-activated compounds.
Used in the Reduction of Amides, Nitriles, and Amines:
Sodium bis(2-methoxyethoxy)aluminiumhydride is involved in the reduction of amides, nitriles, and amines to the corresponding amines.
Used as a Tosyl Deprotecting Agent:
Sodium bis(2-methoxyethoxy)aluminiumhydride can be used as a tosyl deprotecting agent.
Used as a Catalyst for Crosslinking of Polyvinylsilanes (PVS):
Sodium bis(2-methoxyethoxy)aluminiumhydride acts as a catalyst for the crosslinking of polyvinylsilanes (PVS) by Si-Si dehydrocoupling reaction in the presence of group 4 metallocene complexes.
Used as a Reducing Reagent for the Synthesis of Optically Active N-Protected Amino Alcohols and Peptide Alcohols:
Sodium bis(2-methoxyethoxy)aluminiumhydride is used as a reducing reagent for the synthesis of optically active N-protected amino alcohols and peptide alcohols.
Used as a Catalyst in Ring-Opening Polymerization Reactions:
Sodium bis(2-methoxyethoxy)aluminiumhydride is also used as a catalyst in the ring-opening polymerization reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 22722-98-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,7,2 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 22722-98:
(7*2)+(6*2)+(5*7)+(4*2)+(3*2)+(2*9)+(1*8)=101
101 % 10 = 1
So 22722-98-1 is a valid CAS Registry Number.
InChI:InChI=1/2C3H7O2.Al.Na.2H/c2*1-5-3-2-4;;;;/h2*2-3H2,1H3;;;;/q2*-1;2*+1;;/rC6H16AlO4.Na/c1-8-3-5-10-7-11-6-4-9-2;/h3-7H2,1-2H3;/q-1;+1
