2253-69-2Relevant articles and documents
Investigating the microwave-accelerated Claisen rearrangement of allyl aryl ethers: Scope of the catalysts, solvents, temperatures, and substrates
Hui, Zi,Jiang, Songwei,Qi, Xiang,Ye, Xiang-Yang,Xie, Tian
, (2020/05/18)
The microwave-accelerated Claisen rearrangement of allyl aryl ethers was investigated, in order to gain insight into the scope of the catalysts, solvents, temperatures, and substrates. Among the catalysts examined, phosphomolybdic acid (PMA) was found to greatly accelerate the reaction in NMP, at temperatures ranging from 220 to 300 °C. This method was found to be useful for preparing several intermediates previously reported in the literature using precious metal catalysts such as Au(I), Ag(I), and Pt(II). Additionally, substrates bearing bromo and nitro groups on the aryl portion required careful tailoring of the reaction conditions to avoid complex product profiles.
EFFECT OF METAL IONS IN ORGANIC SYNTHESIS. XXXV SIMPLE AND CONVENIENT AROMATIC ALKYLATION OF SOME ALKENYLPHENOL DERIVATIVES WITH tert-ALKYL METHYL ETHERS IN THE PRESENCE OF TIN(IV) CHLORIDE
Attanasi, Orazio A.,Filippone, Paolino,Balducci, Sandro
, p. 487 - 489 (2007/10/02)
A very mild, simple and convenient method for the aromatic alkylation of some alkenylphenol derivatives with tert-alkyl methyl ethers to give sterically hindered phenols useful as antioxidants is reported.The reaction occurs with good yields at room temperature and is promoted by tin(IV) chloride.