22359-67-7

Basic information

• Product Name: 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE
• Synonyms: 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE;(E)-3-(4-METHOXYPHENYL)-1-(NAPHTHALEN-3-YL)PROP-2-EN-1-ONE;(2E)-3-(4-Methoxyphenyl)-1-(2-naphthyl)-2-propen-1-one;1-(2-Naphthyl)-3-(4-methoxyphenyl) prop-2-en-1-one;3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE 97%;3-(4-METHOXYPHENYL)-1-(NAPHTH-2-YL)PROP-2-EN-1-ONE
• CAS NO: 22359-67-7
• Molecular Formula: C₂₀H₁₆O₂
• Molecular Weight: 288.34
• Mol File: 22359-67-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 92 °C
• Boiling Point: 485.9°Cat760mmHg
• Flash Point: 220.6°C
• Appearance: /
• Density: 1.162g/cm³
• Vapor Pressure: 1.35E-09mmHg at 25°C
• Refractive Index: 1.66
• CAS DataBase Reference: 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE(22359-67-7)
• EPA Substance Registry System: 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE(22359-67-7)

Safety Data

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 22359-67-7(Hazardous Substances Data)

Usage

Description

3-(4-Methoxyphenyl)-1-(2-naphthyl)-prop-2-en-1-one is a chemical compound characterized by the molecular formula C20H16O2. It is a yellow solid with a melting point of 122-124°C. 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE is recognized for its potential as a synthetic intermediate in the production of pharmaceuticals and other organic compounds. Additionally, it has demonstrated biological activity, suggesting possible applications in medicine and agriculture. However, further research is necessary to fully explore its properties and potential uses.

Uses

Used in Pharmaceutical Industry:
3-(4-Methoxyphenyl)-1-(2-naphthyl)-prop-2-en-1-one is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure allows it to be a key component in the synthesis of new drugs, potentially leading to advancements in medical treatments.
Used in Organic Compounds Production:
In the field of organic chemistry, 3-(4-Methoxyphenyl)-1-(2-naphthyl)-prop-2-en-1-one serves as an essential intermediate for the synthesis of a range of organic compounds. Its versatility in chemical reactions makes it valuable for creating diverse chemical products.
Used in Medicine:
Due to its biological activity, 3-(4-Methoxyphenyl)-1-(2-naphthyl)-prop-2-en-1-one holds promise for applications in medicine. While further research is required to determine its specific medical uses, its potential impact on healthcare is significant.
Used in Agriculture:
3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE's biological activity also suggests potential applications within the agricultural sector. It may be utilized in the development of new pesticides, herbicides, or other agricultural chemicals to improve crop yields and protect plants from diseases and pests.

InChI:InChI=1/C20H16O2/c1-22-19-11-6-15(7-12-19)8-13-20(21)18-10-9-16-4-2-3-5-17(16)14-18/h2-14H,1H3/b13-8+

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 93-08-3 methyl 2-naphthyl ketone 
• 7228-47-9 2-(2-naphthyl)ethanol 
• 75-05-8 acetonitrile 

Downstream Products

• 113341-19-8 3-(4-Methoxy-phenyl)-5-naphthalen-2-yl-2-naphthalen-1-yl-5-oxo-pentanenitrile 
• 113341-20-1 2-(2,6-Dichloro-phenyl)-3-(4-methoxy-phenyl)-5-naphthalen-2-yl-5-oxo-pentanenitrile 
• 127612-49-1 4-carboethoxy-4-cyano-3,5-di(4-methoxyphenyl)-2-(2-naphthyl)cyclohexanol 
• 127394-78-9 2-Methoxy-4-(4-methoxy-phenyl)-6-naphthalen-2-yl-nicotinonitrile 
• 127394-70-1 2-ethoxy-4-(4-methoxyphenyl)-6-(2-naphthyl)-pyridine-3-carbonitrile 
• 113341-21-2 2-(4-Chloro-phenyl)-3-(4-methoxy-phenyl)-5-naphthalen-2-yl-5-oxo-pentanenitrile 
• 1438279-11-8 (S)-3-(1H-indol-3-yl)-3-(4-methoxyphenyl)-1-(naphthalen-2-yl)propan-1-one 
• 4708-38-7 naphthalen-2-yl-3-(4-methoxyphenyl)oxiran-2-yl-methanone 
• 1402658-91-6 5-(4-methoxyphenyl)-3-(naphthalen-2-yl)-4,5-dihydropyrazole-1-carbothioamide 
• 1402658-59-6 3-{2-[5-(4-methoxyphenyl)-3-naphthalen-2-yl-4,5-dihydropyrazol-1-yl]-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene}-2,3-dihydro-1H-indol-2-one 
• 114346-60-0 C₂₀H₁₈N₂O 
• 1402658-85-8 5-Chloro-3-[5-(4-methoxyphenyl)-3-naphthalen-2-yl-pyrazol-1-yl]-2,3-dihydro-1H-indol-2-one 

Relevant articles and documents

Synthesis, Biological Activity and Action Mechanism Study of Novel Chalcone Derivatives Containing Malonate

A series of novel chalcone malonate derivatives were synthesized and their antibacterial and antiviral activities were evaluated. All target compounds were characterized by spectral data. The results of antimicrobial bioassay showed that one compound (die

Effect of ring A and ring B substitution on the cytotoxic potential of pyrazole tethered chalcones

Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are collectively known as chalcones. The cytotoxic potential of chalcones which consists of C6-C 3-C6 units gets enhanced by the incorporation of pyrazole ring as proved by our earlier studies. Thus in the present work, pyrazoles of chalcones with ring A substituted by furan, naphthalene and variety of substituted phenyl rings has been prepared and evaluated for in vitro cytotoxic activity against PC-3, OVCAR, IMR-32, HEP-2 human cancer cell lines. Springer Science+Business Media, LLC 2011.

Microwave-assisted synthesis of some 3,5-arylated 2-pyrazolines

Condensation of 2-acetylnaphthalene with benzaldehydes under microwave irradiation affords chalcones which undergo facile and clean cyclizations with hydrazines RNHNH2 (R= H, Ph, Ac) to afford 3,5-arylated 2-pyrazolines in quantitative yields,