2219-73-0

Basic information

• Product Name: 4-ethyl-o-cresol
• Synonyms: 4-ethyl-o-cresol;2-Methyl-4-ethylphenol;4-Ethyl-2-methylphenol
• CAS NO: 2219-73-0
• Molecular Formula: C₉H₁₂O
• Molecular Weight: 136.19098
• EINECS: 218-733-1
• Mol File: 2219-73-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 48.26°C (estimate)
• Boiling Point: 227.6°C
• Flash Point: 98.1°C
• Appearance: /
• Density: 0.9809 (estimate)
• Vapor Pressure: 0.0662mmHg at 25°C
• Refractive Index: 1.5134 (estimate)
• PKA: 10.65±0.18(Predicted)
• CAS DataBase Reference: 4-ethyl-o-cresol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethyl-o-cresol(2219-73-0)
• EPA Substance Registry System: 4-ethyl-o-cresol(2219-73-0)

Safety Data

• Hazardous Substances Data: 2219-73-0(Hazardous Substances Data)

Usage

General Description

4-Ethyl-o-cresol, also known as 4-ethyl-2-methylphenol, is a chemical compound with the molecular formula C9H12O. It is a white crystalline solid with a strong odor and is commonly used as a fragrance and flavoring agent. 4-Ethyl-o-cresol is primarily found in essential oils of various plants, including eucalyptus and clove. It is used in the production of perfumes, soaps, and as a flavoring agent in foods and beverages. Additionally, it has antimicrobial properties and is often used as an ingredient in personal care products and pharmaceuticals. However, prolonged exposure to high concentrations of 4-ethyl-o-cresol can cause skin irritation and allergic reactions. Therefore, it is important to handle and use this chemical with caution.

InChI:InChI=1/C9H12O/c1-3-8-4-5-9(10)7(2)6-8/h4-6,10H,3H2,1-2H3

Upstream product

• 7647-01-0 hydrogenchloride 
• 75-07-0 acetaldehyde 
• 64-19-7 acetic acid 
• 95-48-7 ortho-cresol 
• 876-02-8 4-hydroxy-3-methylphenyl methyl ketone 
• 17096-14-9 1,1-bis-(3-methyl-4-hydroxyphenyl)ethane 
• 64-17-5 ethanol 
• 78043-60-4 4-ethyl-1-methyl-4-nitrocyclohexa-2,5-dienyl acetate 

Downstream Products

• 26052-86-8 4-ethyl-2-tert-butyl-6-methyl-phenol 
• 21573-35-3 4-ethyl-2-methylphenyl methyl ether 
• 18606-50-3 1-(3-tert-butyl-4-hydroxy-5-methyl-phenyl)-ethanone 
• 56520-99-1 4-ethyl-2-methyl-6-nitrophenol 
• 104216-48-0 (4-ethyl-2-methyl-phenoxy)-acetic acid 
• 116530-88-2 4-ethyl-2-methyl-cyclohexanol 
• 115322-98-0 2,6-bis-(5-ethyl-2-hydroxy-3-methyl-benzyl)-3,5-dimethyl-phenol 

Relevant articles and documents

Selective hydrodeoxygenation of hydroxyacetophenones to ethyl-substituted phenol derivatives using a FeRu?SILP catalyst

The selective hydrodeoxygenation of hydroxyacetophenone derivatives is achieved opening a versatile pathway for the production of valuable substituted ethylphenols from readily available substrates. Bimetallic iron ruthenium nanoparticles immobilized on an imidazolium-based supported ionic liquid phase (Fe25Ru75?SILP) show high activity and stability for a broad range of substrates without acidic co-catalysts. This journal is

Carboxylic Acid Compounds and Use Thereof

Provision of a superior URAT1 activity inhibitor effective for the treatment and the like of a pathology involving uric acid, such as hyperuricemia, gouty tophus, acute gouty arthritis, chronic gouty arthritis, gouty kidney, urinary lithiasis, renal dysfunction, coronary heart disease, ischemic cardiac diseases and the like. A URAT1 activity inhibitor containing a compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof, or a solvate thereof as an active ingredient: [image] wherein each symbol is as defined in the specification.

CHROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula (I). Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.