2207-50-3

Basic information

• Product Name: AMINOREX
• Synonyms: AMINOREX 4,5-DIHYDRO-5-PHENYL-;4,5-Dihydro-5-phenyl-2-oxazolamine, Aminoxaphen;5-Phenyl-2-oxazolin-2-amine;Apiquel;McN-742;NSC-66952;(5-phenyl-4,5-dihydrooxazol-2-yl)amine;5-phenyl-4,5-dihydro-1,3-oxazol-2-amine
• CAS NO: 2207-50-3
• Molecular Formula: C₉H₁₀N₂O
• Molecular Weight: 162.19
• Product Categories: Amines;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
• Mol File: 2207-50-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 136-138°
• Boiling Point: 288.88°C (rough estimate)
• Flash Point: 2℃
• Appearance: white/solid
• Density: 1.1436 (rough estimate)
• Vapor Pressure: 0.00191mmHg at 25°C
• Refractive Index: 1.5600 (estimate)
• Storage Temp.: ?20°C
• Solubility: 0.1 M HCl: soluble
• PKA: 8.19±0.70(Predicted)
• CAS DataBase Reference: AMINOREX(CAS DataBase Reference)
• NIST Chemistry Reference: AMINOREX(2207-50-3)
• EPA Substance Registry System: AMINOREX(2207-50-3)

Safety Data

• Hazard Codes: T+,Xn,F
• Statements: 26/27/28-36-20/21/22-11
• Safety Statements: 22-36/37/39-45-36/37-26-16
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• RTECS: RQ4500000
• Hazardous Substances Data: 2207-50-3(Hazardous Substances Data)

Usage

Description

AMINOREX, also known as a metabolite of Levamisole, is a compound that has been identified for its various applications across different industries. It is commonly associated with pharmaceutical and medical applications due to its properties and potential effects on the human body.

Uses

Used in Pharmaceutical Industry:
AMINOREX is used as a metabolite for [application reason], which is derived from Levamisole. Its role in this industry is crucial, as it contributes to the development and understanding of various medications and their effects on the human body.
Used in Medical Research:
AMINOREX is used as a research compound for [application reason], aiding in the study of Levamisole and its potential applications in medicine. This helps researchers gain insights into the compound's properties and how it can be utilized for therapeutic purposes.
Brand Names:
AMINOREX is known by several brand names, including Apiquel (Ortho-McNeil), Mcn 742, and Menocil. These names are associated with the compound's use in different products and applications within the pharmaceutical and medical industries.

World Health Organization (WHO)

Aminorex, an anorexic agent, was introduced over twenty years ago for the treatment of obesity. Between 1967 and 1971 its use was associated with cases of pulmonary hypertension which led to its withdrawal in the Federal Republic of Germany. WHO has no information to suggest that this drug remains commercially available.

InChI:InChI=1/C9H10N2O/c10-9-11-6-8(12-9)7-4-2-1-3-5-7/h1-5,8H,6H2,(H2,10,11)

Upstream product

• 506-68-3 bromocyane 
• 7568-93-6 2-Amino-1-phenylethanol 
• 100-52-7 benzaldehyde 

Downstream Products

• 407-24-9 bistrifluoroacetamide 
• 13230-75-6 2,2,2-trifluoro-N-<2-(2,2,2-trifluoroacetyloxy)-2-phenylethyl>acetamide 
• 84353-61-7 1,3-bis(2,2,2-trifluoroacetyl)-1-<2-(2,2,2-trifluoroacetyloxy)-2-phenylethyl>urea 
• 25017-52-1 (2-hydroxy-2-phenylethyl)urea 
• 7693-77-8 5-phenyloxazolidin-2-one 
• 27129-51-7 1-(2-amino-5-phenyl-oxazolidin-2-yl)-1-styryl-urea 
• 62226-13-5 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid 5-phenyl-4,5-dihydro-oxazol-2-ylamide 

Relevant articles and documents

4,5-Disubstituted-1,3-oxazolidin-2-imine derivatives: A new class of orally bioavailable nitric oxide synthase inhibitor

In our search for a novel class of inducible nitric oxide synthase (iNOS) inhibitors, 1,3-oxazolidin-2-imine was found to weakly inhibit iNOS. Further modifications of this compound resulted in a remarkable increase in both the in vivo and in vitro inhibi

Appetite depressants, new method for synthesis of 2-amino-2-oxazoline derivatives

-