21958-32-7Relevant articles and documents
Palladium catalyzed chemo- and site-selective C-H acetoxylation and hydroxylation of oxobenzoxazine derivatives
Bakthadoss, Manickam,Vijay Kumar, Polu,Kumar, Ravan,Agarwal, Vishal
supporting information, p. 4465 - 4469 (2019/05/16)
An efficient protocol for the introduction of acetoxy and hydroxy functionalities on unactivated aryl sp2 carbons of oxobenzoxazine derivatives via an ortho-C-H activation reaction using a palladium catalyst has been developed for the first tim
Studies on Quinazolinones as Dual Inhibitors of Pgp and MRP1 in Multidrug Resistance
Wang, Shouming,Ryder, Hamish,Pretswell, Ian,Depledge, Paul,Milton, John,Hancox, Timothy C.,Dale, Ian,Dangerfield, Wendy,Charlton, Peter,Faint, Richard,Dodd, Rory,Hassan, Stephanie
, p. 571 - 574 (2007/10/03)
The syntheses and SAR studies of various quinazolinone compounds are described for the dual inhibition of Pgp and MRP1 in multidrug resistance.
Synthesis and evaluation of 2-aryl-4H-3,1-benzoxazin-4-ones as C1r serine protease inhibitors
Gilmore, John L.,Hays, Sheryl J.,Caprathe, Bradley W.,Lee, Chitase,Emmerling, Mark R.,Michael, Walter,Jaen, Juan C.
, p. 679 - 682 (2007/10/03)
A series of 2-aryl-4H-3,1-benzoxazin-4-ones have been synthesized and tested for inhibitory activity against C1r serine protease. Compounds were found that were equipotent and more selective than the reference compound FUT-175.
