21388-92-1

Basic information

• Product Name: Benzenemethanol, 4-bromo-, acetate
• Synonyms: Benzenemethanol, 4-bromo-, acetate (9CI);Benzyl alcohol, p-bromo-, acetate (6CI,8CI);4-(Acetoxymethyl)bromobenzene
• CAS NO: 21388-92-1
• Molecular Formula: C₉H₉BrO₂
• Molecular Weight: 229.073
• Mol File: 21388-92-1.mol
• Article Data: 53

Chemical Properties

• Boiling Point: 265.397 °C at 760 mmHg
• Flash Point: 114.309 °C
• Density: 1.446 g/cm³
• CAS DataBase Reference: Benzenemethanol, 4-bromo-, acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-bromo-, acetate(21388-92-1)
• EPA Substance Registry System: Benzenemethanol, 4-bromo-, acetate(21388-92-1)

Safety Data

• Hazardous Substances Data: 21388-92-1(Hazardous Substances Data)

Usage

Description

Benzenemethanol, 4-bromo-, acetate is a chemical compound characterized by the molecular formula C9H9BrO2. It is a colorless liquid with a molecular weight of 227.07 g/mol. Benzenemethanol, 4-bromo-, acetate is commonly utilized in organic synthesis and pharmaceutical research as a reagent for preparing various organic compounds. Benzenemethanol, 4-bromo-, acetate is also recognized as a precursor in the production of pharmaceuticals and agrochemicals. Known by its CAS number 5026-62-0, it is classified as a hazardous substance, necessitating careful handling and storage.

Uses

Used in Pharmaceutical Research:
Benzenemethanol, 4-bromo-, acetate is employed as a reagent in pharmaceutical research for the preparation of various organic compounds. Its unique structure and properties make it a valuable component in the synthesis of new pharmaceutical agents.
Used in Agrochemical Production:
Benzenemethanol, 4-bromo-, acetate is also used as a precursor in the production of agrochemicals, contributing to the development of new pesticides and other agricultural products that can enhance crop protection and yield.
Used in Organic Synthesis:
Benzenemethanol, 4-bromo-, acetate plays a crucial role in organic synthesis, where it serves as a building block for the creation of a wide range of organic compounds, including those with potential applications in various industries.

Upstream product

• 106-38-7 para-bromotoluene 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 873-75-6 4-bromobenzenemethanol 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 57477-93-7 hydrazone of p-bromobenzaldehyde 
• 108-05-4 vinyl acetate 
• 130534-91-7 1-bromo-4-[(methoxymethyloxy)methyl]benzene 
• 216443-67-3 4-bromo-1-[(ethoxymethoxy)methyl]benzene 
• 75-36-5 acetyl chloride 
• 141-78-6 ethyl acetate 
• 86605-93-8 (4-bromobenzyloxy)trimethylsilane 
• 127-09-3 sodium acetate 
• 589-15-1 1-bromomethyl-4-bromobenzene 

Downstream Products

• 873-75-6 4-bromobenzenemethanol 
• 1301606-98-3 {2'-{1-(p-methoxybenzyl)-1H-tetrazol-5-yl}biphenyl-4-yl}methyl acetate 
• 1307853-43-5 (2'-(1-benzyl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl acetate 
• 1627211-36-2 4-(1-(N,N-dimethylsulfamoyl)-1H-pyrazol-5-yl)benzyl acetate 
• 1417451-66-1 2,2':6,2-terpyridineethynylbenzyl mesylate 
• 1417451-65-0 2,2':6,2-terpyridineethynylbenzyl alcohol 
• 1417451-54-7 2,2':6,2-terpyridineethynylbenzyl azide 
• 863560-90-1 acetic acid 4-ethynyl-benzyl ester 
• 1041297-60-2 acetic acid 4-trimetylsilanylethynyl-benzyl ester 
• 1294447-50-9 C₁₅H₉F₁₃O₂ 
• 1294447-52-1 C₁₇H₁₁F₁₃O₂ 
• 389873-33-0 4-(tridecafluorohex-1-yl)benzyl alcohol 
• 1301606-99-4 1-((2'-(1-(2-methoxybenzyl)-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)oxy)propan-2-one 
• 137862-53-4 N-pentanoyl-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]-methyl]-(L)-valine 

Relevant articles and documents

Bu 4 NI-Catalyzed C-C Bond Cleavage and Oxidative Esteri??cation of Allyl Alcohols with Toluene Derivatives

A novel oxidative esterification of 1-arylprop-2-en-1-ols with toluene derivatives catalyzed by tetrabutylammonium iodide (TBAI) is reported. The optimization of the reaction conditions illustrates that each of experiment parameters including the catalyst, solvent, and oxidant is significant for present oxidative functionalization. This metal-free protocol has a broad substrate scope including the halogen groups for further functionalization and enriches the reactivity profile of allyl alcohol and toluene derivatives. In addition, this protocol represents a new transformation of allyl alcohol involving C-C bond cleavage and C-O bond forming.

Acylation of Phenols, Alcohols, Thiols, Amines and Aldehydes Using Sulfonic Acid Functionalized Hyper-Cross-Linked Poly(2-naphthol) as a Solid Acid Catalyst

Abstract: The hyper-cross-linked porous poly(2-naphthol) fabricated by the Friedel–Crafts alkylation of 2-naphthol has been functionalized with sulfonic acid to obtain a solid acid catalyst. The catalyst is applied for the protection of phenol, alcohols, thiols, amines and aldehydes with acetic anhydride at room temperature. The catalytic protection using the new solid acid is featured by achieving high yield at neat condition, needing no aqueous work-up and/or chromatographic separation, and showing excellent recycling efficiency, suggesting the potential of this sulfonated porous polymers as a new protection protocol in a wide range of sustainable chemical reactions. Graphical Abstract: [Figure not available: see fulltext.].

Preparation of Polydopamine Sulfamic Acid-Functionalized Silica Gel as Heterogeneous and Recyclable Nanocatalyst for Acetylation of Alcohols and Amines Under Solvent-Free Conditions

To fabricate SiO2/PDA–SO3H nanocatalyst, a suitable method is designed for the loading of sulfonic acid groups on the surface of polydopamine (PDA)-encapsulated SiO2 nanoparticles. To bridge the gap between heterogeneous and homogeneous catalysis, surface functionalization of silica gel is an elegant procedure. The morphology, structure, and physicochemical features were specified using different analytical techniques including field emission scanning electron microscopy (FESEM), Fourier transformed infrared spectroscopy (FT-IR), high resolution-transmission electron microscopy (HR-TEM), energy dispersive X-ray spectroscopy (EDS), wavelength-dispersive X-ray spectroscopy (WDX), X-ray photoelectron spectroscopy (XPS), and back titration. The SiO2/PDA–SO3H nanoparticles are efficient nanocatalysts for the acetylation of many alcohols, phenols, and amines with acetic anhydride under solvent-free conditions in good to excellent yields. Moreover, the reuse and recovery of the catalyst was shown seven times without detectible loss in activity. Graphical Abstract: [Figure not available: see fulltext.]