213481-01-7Relevant articles and documents
Coumarin base-pair replacement as a fluorescent probe of ultrafast DNA dynamics
Coleman, Robert S.,Berg, Mark A.,Murphy, Catherine J.
, p. 3450 - 3456 (2007)
The design and synthesis of a novel coumarin C-riboside are described, and is based on the well-known photoprobe Coumarin 102. A diastereofacial selective Heck coupling between a furanoid glycal and a coumarin triflate provided a method for glycoside formation. The coumarin C-glycoside was incorporated synthetically into DNA oligomers, and was used to probe ultrafast dynamics of duplex DNA using time-resolved Stokes shift methods.
Straightforward access to water-soluble unsymmetrical sulfoxanthene dyes: Application to the preparation of far-red fluorescent dyes with large stokes' shifts
Chevalier, Arnaud,Renard, Pierre-Yves,Romieu, Anthony
supporting information, p. 8330 - 8337 (2014/07/08)
An efficient synthesis of water-soluble unsymmetrical sulforhodamine/ sulforhodol fluorophores containing a single julolidine fragment is presented. Owing to their valuable spectral properties in aqueous buffers, these dyes, especially those bearing a free aniline or phenol moiety, are valuable components of fluorogenic probes for a variety of biosensing applications. A further extension of this synthetic methodology to unusual phenols, namely 7-N,N-dialkylamino-4-hydroxy coumarins has enabled us to provide a new family water-soluble dyes of large Stokes' shift with far-red spectral features.