213343-65-8 Usage
Description
(-)-1,2-BIS((2S,5S)-2,5-DIMETHYLPHOSPHOLANO)ETHANE(CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE, commonly known as DuPhos, is a chiral rhodium (I) complex that serves as a highly efficient and versatile ligand in various catalytic applications. It is characterized by its unique structure, featuring a cyclooctadiene moiety and two (2S,5S)-2,5-dimethylphospholano groups, which contribute to its exceptional catalytic performance.
Uses
Used in Pharmaceutical Industry:
DuPhos is used as a privileged ligand for asymmetric hydrogenation, a key reaction in the synthesis of chiral pharmaceutical compounds. Its high efficiency and selectivity make it an ideal choice for the production of enantiomerically pure drugs, ensuring the desired biological activity and minimizing potential side effects.
Used in Chemical Synthesis:
In the field of chemical synthesis, DuPhos is employed as a catalyst for asymmetric hydrogenation reactions, enabling the selective formation of chiral compounds with high enantioselectivity. This is particularly important in the synthesis of complex organic molecules, such as natural products and agrochemicals, where the stereochemistry of the product can significantly impact its biological activity.
Used in Research and Development:
DuPhos is also utilized in academic and industrial research settings as a valuable tool for studying the mechanisms of asymmetric catalysis and developing new catalytic systems. Its unique structure and properties allow chemists to gain insights into the factors that govern enantioselectivity and to design new ligands with improved performance.
Overall, (-)-1,2-BIS((2S,5S)-2,5-DIMETHYLPHOSPHOLANO)ETHANE(CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE, or DuPhos, is a highly efficient and versatile ligand with a wide range of applications in the synthesis of chiral compounds, particularly in the pharmaceutical industry, chemical synthesis, and research and development. Its exceptional performance in asymmetric hydrogenation reactions makes it a valuable asset in the development of enantiomerically pure products.
Check Digit Verification of cas no
The CAS Registry Mumber 213343-65-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,3,3,4 and 3 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 213343-65:
(8*2)+(7*1)+(6*3)+(5*3)+(4*4)+(3*3)+(2*6)+(1*5)=98
98 % 10 = 8
So 213343-65-8 is a valid CAS Registry Number.
