211690-33-4

Basic information

• Product Name: LOMEFLOXACIN, ASPARTATE
• Synonyms: LOMEFLOXACIN, ASPARTATE;1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid L-Aspartate;1-Ethyl-6,8-difluoro-7-(3-Methyl-1-piperazinyl)-4-oxo-1,4 -dihydro-3-quinoline carboxylic Acid L-Aspartate;DM 10 L-Aspartate;SC 47111A L-Aspartate;(S)-2-Aminosuccinic acid 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoli;(S)-2-Aminosuccinic acid 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquin;(2S)-2-aminobutanedioic acid,1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
• CAS NO: 211690-33-4
• Molecular Formula: C17H19F2N3O3.C4H7NO4
• Molecular Weight: 484.453
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 211690-33-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• CAS DataBase Reference: LOMEFLOXACIN, ASPARTATE(CAS DataBase Reference)
• NIST Chemistry Reference: LOMEFLOXACIN, ASPARTATE(211690-33-4)
• EPA Substance Registry System: LOMEFLOXACIN, ASPARTATE(211690-33-4)

Safety Data

• Hazardous Substances Data: 211690-33-4(Hazardous Substances Data)

Usage

Uses

Fluorinated quinolone antibacterial. DNA gyrase antagonist

InChI:InChI=1S/C17H19F2N3O3.C4H7NO4/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22;5-2(4(8)9)1-3(6)7/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25);2H,1,5H2,(H,6,7)(H,8,9)/t;2-/m.0/s1

Upstream product

• 56-84-8 L-Aspartic acid 
• 98079-51-7 Lomefloxacin hydrochloride 

Relevant articles and documents

Preparation method of lomefloxacin aspartate

The invention relates to a preparation method of an anti-infectious agent, particularly relates to a preparation method of lomefloxacin aspartate. The preparation method comprises the steps of performing a neutralization reaction on lomefloxacin hydrochloride, water and an alkaline solution in proportion, obtaining lomefloxacin base, performing a salt forming reaction on the lomefloxacin base generated by the neutralization reaction, L-aspartate and the water in proportion, obtaining a lomefloxacin aspartate wet product, refining the lomefloxacin base, the L-aspartate and mother liquor obtained by a purified water salt forming reaction, obtaining the lomefloxacin aspartate wet product, and finally drying the lomefloxacin aspartate wet product, so as to obtain a finished product, generally, the preparation method has the advantages that the lomefloxacin aspartate can react in the water, the production cost can be effectively reduced, the reaction speed can be improved, the safety in the production process can be improved, the economic benefit of enterprise can be improved, and a high use value can be realized.