20972-37-6Relevant articles and documents
Comparison of the Photochemistry of Acyclic and Cyclic 4-(4-Methoxy-phenyl)-4-oxo-but-2-enoate Ester Derivatives
Abdelaziz, Nayera M.,Day, Heidi A.,Gudmundsdottir, Anna D.,Krause, Jeanette A.,Merugu, Rajkumar,Robinson, Jendai,Sarkar, Sujan K.,Upul Ranaweera, Ranaweera A. A.
, p. 7346 - 7354 (2020)
To clarify the cis-trans isomerization mechanism of simple alkenes on the triplet excited state surface, the photochemistry of acyclic and cyclic vinyl ketones with a p-methoxyacetophenone moiety as a built-in triplet sensitizer (1 and 2, respectively) wa
Base-Promoted Annulative Difluoromethylenation of Enaminones with BrCF2CO2Et toward 2,2-Difluorinated 2,3-Dihydrofurans
Ying, Jinbiao,Liu, Ting,Liu, Yunyun,Wan, Jie-Ping
, p. 2404 - 2408 (2022/04/07)
A practical method for the synthesis of 2,2-difluorinated 2,3-dihydrofurans has been established via the [4 + 1] annulation of enaminones and BrCF2CO2Et with Na2CO3 promotion. This new protocol does not employ any transition metal reagent and enables the annulative difluoromethylation by the partial cleavage of the C═C double bond. In addition, the further treatment with hydrochloric acid in one pot leads to β-keto enoic acids (4-oxo-2-butenoic acids) via a formal enaminone C-N carboxylation.
Isocyanide-based MCRs: Diastereoselective cascade synthesis of perfluoroalkylated pyrano[3,4-c]pyrrole derivatives
Yang, Shanxue,Yao, Lan,Fan, Zhenhua,Han, Jing,Chen, Jie,He, Weimin,Deng, Hongmei,Shao, Min,Zhang, Hui,Cao, Weiguo
supporting information, (2021/02/03)
The highly diastereoselective synthesis of perfluoroalkyl-containing pyrano[3,4-c]pyrroles has been accomplished via a cascade process involving Michael addition, Passerini-type reaction, Mumm rearrangement and an oxo-Diels–Alder reaction. This domino tra