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199328-35-3

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199328-35-3 Usage

General Description

Benzeneacetic Acid, 4-Bromo-2-Nitro-, Ethyl Ester is a synthetic chemical with the molecular formula C10H10BrNO4. It is largely used in the pharmaceutical industry for making various types of drugs. The chemical is white to light yellow in colour and generally appears in crystalline or powder form. It is non-flammable but can emit toxic fumes when heated, and direct contact may cause skin and eye irritation. Handling it requires safety equipment due to its harmful nature.

Check Digit Verification of cas no

The CAS Registry Mumber 199328-35-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,3,2 and 8 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 199328-35:
(8*1)+(7*9)+(6*9)+(5*3)+(4*2)+(3*8)+(2*3)+(1*5)=183
183 % 10 = 3
So 199328-35-3 is a valid CAS Registry Number.

199328-35-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-(4-bromo-2-nitrophenyl)acetate

1.2 Other means of identification

Product number -
Other names FC1042

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:199328-35-3 SDS

199328-35-3Relevant articles and documents

FUSED RING COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

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, (2014/06/23)

Provided are fused tricyclic compounds effective to inhibit the function of the NS5A protein of formula (I), wherein X, X', Y, Y', A, A',Q1, Q2, R1-R4, X4, R5a, f and W are defined as in the description. Also provided herein are pharmaceutical compositions thereof, and uses in the manufacture of a medicament for treating HCV infection or a HCV disorder thereof.

Discovery of GNF-5837, a selective TRK inhibitor with efficacy in rodent cancer tumor models

Albaugh, Pam,Fan, Yi,Mi, Yuan,Sun, Fangxian,Adrian, Francisco,Li, Nanxin,Jia, Yong,Sarkisova, Yelena,Kreusch, Andreas,Hood, Tami,Lu, Min,Liu, Guoxun,Huang, Shenlin,Liu, Zuosheng,Loren, Jon,Tuntland, Tove,Karanewsky, Donald S.,Seidel, H. Martin,Molteni, Valentina

, p. 140 - 145 (2012/04/10)

Neurotrophins and their receptors (TRKs) play key roles in the development of the nervous system and the maintenance of the neural network. Accumulating evidence points to their role in malignant transformations, chemotaxis, metastasis, and survival signaling and may contribute to the pathogenesis of a variety of tumors of both neural and non-neural origin. By screening the GNF kinase collection, a series of novel oxindole inhibitors of TRKs were identified. Optimization led to the identification of GNF-5837 (22), a potent, selective, and orally bioavailable pan-TRK inhibitor that inhibited tumor growth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF. The properties of 22 make it a good tool for the elucidation of TRK biology in cancer and other nononcology indications.

Monofluoroalkyl derivatives

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Page/Page column 93, (2010/10/20)

The present invention provides certain monofluoroalkyl derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.

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