1969289-10-8 Usage
Description
(-)-Celosine, a pyrrolidine alkaloid compound, is naturally found in the plant Celosia argentea. It has been recognized for its potential bioactivity and diverse pharmacological properties, including significant anti-inflammatory and antioxidant activities. These characteristics position (-)-celosine as a promising candidate for the development of therapeutic agents targeting inflammatory conditions and oxidative stress-related diseases. Moreover, its demonstrated cytotoxic effects on specific cancer cell lines suggest its potential as a chemotherapeutic agent, warranting further research to uncover its full spectrum of biological activities and applications.
Uses
Used in Pharmaceutical Industry:
(-)-Celosine is used as a potential therapeutic agent for its anti-inflammatory properties, aiming to treat various inflammatory conditions. Its antioxidant activities also make it a candidate for developing treatments for oxidative stress-related diseases.
Used in Oncology:
(-)-Celosine is used as a potential chemotherapeutic agent due to its cytotoxic effects against certain cancer cell lines, indicating its capacity to be further explored and developed for cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 1969289-10-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,9,6,9,2,8 and 9 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1969289-10:
(9*1)+(8*9)+(7*6)+(6*9)+(5*2)+(4*8)+(3*9)+(2*1)+(1*0)=248
248 % 10 = 8
So 1969289-10-8 is a valid CAS Registry Number.
1969289-10-8Relevant articles and documents
Isolation, structure elucidation, and KDD study of (-)-Celosine, a new skeleton with potent anti-atherosclerosis activity
Sun, Zhenliang,Lv, Zhiliang,Hu, Bin,Zhang, Jifa,Du, Peng,Wang, Man,Xiao, Linlin,Yang, Peiming
, p. 50875 - 50879 (2017/11/10)
Natural (-)-Celosine was isolated as a novel endocyclicditerpene with an unprecedented skeleton from Celosia cristata L. Its structure was established by comprehensive 1D and 2D NMR spectroscopic analysis in combination with single-crystal X-ray crystallographic diffraction of synthesized (+)-Celosine. (-)-Celosine was expected to have an anti-atherosclerotic activity in vivo, and myeloperoxidase (MPO) expression may be the mechanism underlying this anti-atherosclerotic activity.
