192064-71-4

Basic information

• Product Name: (E)-5-(trimethylsilanyl)pent-4-en-1-ol
• Synonyms: (E)-5-(trimethylsilanyl)pent-4-en-1-ol
• CAS NO: 192064-71-4
• Molecular Weight: 158.316
• Mol File: 192064-71-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-5-(trimethylsilanyl)pent-4-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-5-(trimethylsilanyl)pent-4-en-1-ol(192064-71-4)
• EPA Substance Registry System: (E)-5-(trimethylsilanyl)pent-4-en-1-ol(192064-71-4)

Safety Data

• Hazardous Substances Data: 192064-71-4(Hazardous Substances Data)

Upstream product

• 5272-36-6 3-trimethylsilyl-2-propyn-1-ol 
• 198410-89-8 (Z)-5-dimethylphenylsilyl-5-trimethylsilyl-4-penten-1-ol 

Downstream Products

• 1404098-91-4 (5S,8S,9S,E)-5-(dimethyl(phenyl)silyl)-10-ethoxy-6-methyl-5-(trimethylsilyl)dec-6-ene-1,9-diol 
• 1404099-03-1 (5R,8S,9S,E)-5-(dimethyl(phenyl)silyl)-10-ethoxy-6-methyl-5-(trimethylsilyl)dec-6-ene-1,9-diol 
• 1404098-90-3 (5S,8S,9S,E)-5-(dimethyl(phenyl)silyl)-10-methoxy-6-methyl-5-(trimethylsilyl)dec-6-ene-1,9-diol 
• 1404099-02-0 (5R,8S,9S,E)-5-(dimethyl(phenyl)silyl)-10-methoxy-6-methyl-5-(trimethylsilyl)dec-6-ene-1,9-diol 

Relevant articles and documents

Anti-hydroalumination of homo- and bishomopropargyl alcohols

The reaction of ω-Me3Si- or ω-Me3Ge-substituted 3-butyn-1-ol, 4-pentyn-1-ol, and their derivatives with DIBAL-H and a small trialkylalane, e.g., Me3Al or Et3Al, at 23°C gives, after iodinolysis, the corresponding (Z)-4-iodo-3-buten-1-ols and (Z)-5-iodo-4-penten-1-ols in a highly stereo- and regio-selective manner, most probably via endo-dig mode cyclic anti-hydroalumination, while treatment of ω-carbosubstituted 3-butyn-1-ols with Red-Al or LialH4 at high temperatures followed by iodinolysis can give the corresponding (Z)-4-iodo-3-buten-1-ols also in a highly regio- and stereoselective manner.