19046-60-7 Usage
Description
ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE is a colorless to white crystalline compound that serves as an intermediate in the biochemical conversion between glucose and galactose. It is derived from the natural sugar, alpha-D-galactose, which is found in various organisms, including bacteria, plants, animals, and human brains. ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE is produced from galactose by the enzyme galactokinase and plays a crucial role in the metabolic pathway involving the reversible catalysis of UDP-glucose and galactose-1-phosphate to glucose-1-phosphate and UDP-galactose by galactose-1-phosphate uridyl transferase.
Uses
Used in Pharmaceutical Industry:
ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly those targeting metabolic disorders related to glucose and galactose metabolism. Its role in the interconversion of glucose and galactose makes it a valuable compound for developing therapies for conditions such as galactosemia, a genetic disorder characterized by the inability to metabolize galactose.
Used in Research and Development:
In the field of research and development, ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE is utilized as a vital component in the study of glucose and galactose metabolism, as well as the enzymes involved in these processes. It aids in understanding the underlying mechanisms of various metabolic pathways and contributes to the development of novel therapeutic strategies for related diseases.
Used in Biochemical Assays:
ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE is employed as a substrate or standard in various biochemical assays designed to measure the activity of enzymes involved in glucose and galactose metabolism. These assays are essential for evaluating the effectiveness of potential therapeutic agents and for monitoring enzyme activity in research settings.
Used in Nutritional Supplements:
As a component of the metabolic pathway involving glucose and galactose, ALPHA-D-GALACTOSE-1-PHOSPHATE DIPOTASSIUM SALT DIHYDRATE may be used in the development of nutritional supplements aimed at supporting healthy glucose and galactose metabolism. These supplements could potentially benefit individuals with metabolic disorders or those looking to maintain optimal metabolic function.
Check Digit Verification of cas no
The CAS Registry Mumber 19046-60-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,0,4 and 6 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 19046-60:
(7*1)+(6*9)+(5*0)+(4*4)+(3*6)+(2*6)+(1*0)=107
107 % 10 = 7
So 19046-60-7 is a valid CAS Registry Number.
19046-60-7Relevant articles and documents
Facile enzymatic synthesis of sugar 1-phosphates as substrates for phosphorylases using anomeric kinases
Liu, Yuan,Nishimoto, Mamoru,Kitaoka, Motomitsu
, p. 1 - 4 (2015/02/19)
Three sugar 1-phosphates that are donor substrates for phosphorylases were produced at the gram scale from phosphoenolpyruvic acid and the corresponding sugars by the combined action of pyruvate kinase and the corresponding anomeric kinases in good yields. These sugar 1-phosphates were purified through two electrodialysis steps. α-d-Galactose 1-phosphate was finally isolated as crystals of dipotassium salts. α-d-Mannose 1-phosphate and 2-acetamido-2-deoxy-α-d-glucose 1-phosphate were isolated as crystals of bis(cyclohexylammonium) salts.
