189180-18-5

Basic information

• Product Name: Phosphonic acid, [amino(2-chlorophenyl)methyl]-, diethyl ester
• CAS NO: 189180-18-5
• Molecular Formula: C11H17ClNO3P
• Molecular Weight: 277.688
• Mol File: 189180-18-5.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [amino(2-chlorophenyl)methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [amino(2-chlorophenyl)methyl]-, diethyl ester(189180-18-5)
• EPA Substance Registry System: Phosphonic acid, [amino(2-chlorophenyl)methyl]-, diethyl ester(189180-18-5)

Safety Data

• Hazardous Substances Data: 189180-18-5(Hazardous Substances Data)

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 762-04-9 phosphonic acid diethyl ester 
• 16712-16-6 ammonium formate 
• 762-04-9 Diethyl phosphonate 
• 932-72-9 (Dichloroiodo)benzene 

Downstream Products

• 1260249-28-2 C₂₆H₃₁ClN₃O₈P 
• 1454615-06-5 C₃₂H₄₄ClN₂O₄PS 
• 1621069-76-8 O,O′-diethyl (2-chlorophenyl)(2-(1-hydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yloxy)propanamido)methylphosphonate 
• 1621069-68-8 O,O′-diethyl (2-chlorophenyl)(2-(1-hydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yloxy)acetamido)methylphosphonate 
• 1533457-16-7 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(2-chlorophenyl)methylphosphonate 
• 1254692-37-9 C₁₅H₁₉ClN₃O₄PS 
• 1218951-10-0 O,O-diethyl N-[2-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yloxy)benzoxyl]-1-amino-1-(2-chlorophenyl)methyl phosphonate 

Relevant articles and documents

Synthesis of derivatives of artesunate α-aminophosphonate and their antimicrobial activities

Thirteen α-aminophosphonate derivatives with artesunate were synthesized by introducing bioactive α-aminophosphonate combination with artesunate in this work. The reaction were easily carried out at normal pressure, low temperature and without any catalys

Coumarin-containing aminophosphonates bridged with chiral side chain: Synthesis and influence of chirality on cytotoxicity and DNA binding

A series of novel coumarin-containing α-Aminophosphonates with two chiral centers were synthesized and a single-crystal structure of compound 8g (8g', (R)-diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(2- bromophenyl)methylphosphonate) was

Synthesis and antitumor activities of novel rhein α-aminophosphonates conjugates

Several rhein α-aminophosphonates conjugates (5a-5q) were synthesized and evaluated for in vitro cytotoxicity against HepG-2, CNE, Spca-2, Hela and Hct-116 cell lines. Some compounds showed relatively high cytotoxicity. Especially, compound 5i exhibited t