18698-97-0 Usage
Description
2-Bromophenylacetic acid is an organic compound that appears as almost white to light beige crystals or powder. It is a derivative of phenylacetic acid with a bromine atom attached to the benzene ring, which imparts unique chemical properties to the molecule.
Uses
Used in Pharmaceutical Industry:
2-Bromophenylacetic acid is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its unique chemical structure allows it to be a key component in the development of new pharmaceutical compounds.
Used in Organic Synthesis:
2-Bromophenylacetic acid is also used in organic synthesis as a starting reagent. It serves as a building block for the creation of more complex organic molecules, which can be used in various applications, including the development of new materials and chemicals.
Used in Synthesis of 8-Methoxy-2-Tetralone:
2-Bromophenylacetic acid is used as a starting reagent in the synthesis of 8-methoxy-2-tetralone, a compound with potential applications in the pharmaceutical industry.
Used in Preparation of Di-and Tri-Substituted 2-Oxopiperazines on Solid Support:
In the field of organic chemistry, 2-bromophenylacetic acid is utilized in the preparation of di-and tri-substituted 2-oxopiperazines on solid support. This application highlights its versatility as a synthetic building block in the creation of diverse chemical structures.
Synthesis Reference(s)
The Journal of Organic Chemistry, 49, p. 4226, 1984 DOI: 10.1021/jo00196a024
Check Digit Verification of cas no
The CAS Registry Mumber 18698-97-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,6,9 and 8 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18698-97:
(7*1)+(6*8)+(5*6)+(4*9)+(3*8)+(2*9)+(1*7)=170
170 % 10 = 0
So 18698-97-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H7BrO2/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5H2,(H,10,11)/p-1
18698-97-0Relevant articles and documents
-
Dippy,Williams
, p. 1888,1889 (1934)
-
Macrolactam Synthesis via Ring-Closing Alkene-Alkene Cross-Coupling Reactions
Goh, Jeffrey,Loh, Teck-Peng,Maraswami, Manikantha
supporting information, p. 9724 - 9728 (2020/12/21)
Reported herein is a practical method for macrolactam synthesis via a Rh(III)-catalyzed ring closing alkene-alkene cross-coupling reaction. The reaction proceeded via a Rh-catalyzed alkenyl sp2 C-H activation process, which allows access to macrocyclic molecules of different ring sizes. Macrolactams containing a conjugated diene framework could be easily prepared in high chemoselectivities and Z,E stereoselectivities.
Double Functionalization of Styrenes by Cu-Mediated Assisted Tandem Catalysis
Kawauchi, Daichi,Ueda, Hirofumi,Tokuyama, Hidetoshi
supporting information, p. 2056 - 2060 (2019/03/13)
The double functionalization of styrenes through Cu-mediated assisted tandem catalysis was developed. The reaction was initiated by Cu-catalyzed aziridination and the subsequent nucleophilic ring-opening, which was triggered by the addition of (NH4)2S2O8 as an oxidant of Cu-catalyst to form a variety of C–C and C–X bonds. The expansion to three contiguous catalytic cycles led to the synthesis of functionalized indolines by one-pot operation.
