186139-09-3 Usage
General Description
Cholestane-7,24-diol, 3-((3-((4-((3-aminopropyl)amino)butyl)amino)propyl)amino)-, 24-(hydrogen sulfate), (3beta,5alpha,7alpha,24R)- is a complex chemical compound that belongs to the class of steroids. It is a derivative of cholestane and contains multiple amine functional groups, as well as a hydrogen sulfate group. The compound has a specific stereochemistry, with a 3β,5α,7α,24R configuration. This chemical may have potential applications in pharmaceutical research, due to its structural complexity and potential biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 186139-09-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,1,3 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 186139-09:
(8*1)+(7*8)+(6*6)+(5*1)+(4*3)+(3*9)+(2*0)+(1*9)=153
153 % 10 = 3
So 186139-09-3 is a valid CAS Registry Number.
186139-09-3Relevant articles and documents
Aminosterols from the dogfish shark Squalus acanthias
Rao, Meenakshi N.,Shinnar, Ann E.,Noecker, Lincoln A.,Chao, Tessa L.,Feibush, Binyamin,Snyder, Brad,Sharkansky, Ilya,Sarkahian, Ani,Zhang, Xuehai,Jones, Stephen R.,Kinney, William A.,Zasloff, Michael
, p. 631 - 635 (2000)
Seven new aminosterols related to squalamine (8) were isolated from the liver of the dogfish shark Squalus acanthias. Their structures (1-7) were determined using spectroscopic methods, including 2D NMR and HRFABMS. These aminosterols possess a relatively invariant cholestane skeleton with a trans AB ring junction, a spermidine or spermine attached equatorially at C3, and a steroidal side-chain that may be sulfated. The structure of the lone spermine conjugate, 7 (MSI-1436), was confirmed by its synthesis from (5α,7α,24R)-7- hydroxy-3-ketocholestan-24-yl sulfate. Some members of this family of aminosterols exhibit a broad spectrum of antimicrobial activity comparable to squalamine.
