185611-87-4

Basic information

• Product Name: (S)-3-(Bis-allyloxy-phosphoryloxy)-2-[(S)-2-((S)-4-methyl-2-phenylacetylamino-pentanoylamino)-propionylamino]-propionic acid tert-butyl ester
• CAS NO: 185611-87-4
• Molecular Weight: 623.684
• Mol File: 185611-87-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-(Bis-allyloxy-phosphoryloxy)-2-[(S)-2-((S)-4-methyl-2-phenylacetylamino-pentanoylamino)-propionylamino]-propionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(Bis-allyloxy-phosphoryloxy)-2-[(S)-2-((S)-4-methyl-2-phenylacetylamino-pentanoylamino)-propionylamino]-propionic acid tert-butyl ester(185611-87-4)
• EPA Substance Registry System: (S)-3-(Bis-allyloxy-phosphoryloxy)-2-[(S)-2-((S)-4-methyl-2-phenylacetylamino-pentanoylamino)-propionylamino]-propionic acid tert-butyl ester(185611-87-4)

Safety Data

• Hazardous Substances Data: 185611-87-4(Hazardous Substances Data)

Upstream product

• 126429-21-8 diallyl diisopropylphosphoramidite 

Relevant articles and documents

Selective enzymatic removal of protecting groups: The phenylacetamide as amino protecting group in phosphopeptide synthesis

The phenylacetamido (PhAc) amino protecting group can be removed from sensitive phosphopeptides by means of penicillin G acylase under mild conditions (pH 6.5, room temperature) and without attack on the peptide bonds, the C-terminal esters or the phosphates. In particular, under the conditions of the enzymatic reactions a β-elimination of the phosphate does not occur.