181811-68-7

Basic information

• Product Name: 1,2-dihydro-6-(4-fluorophenyl)-5-[4-(methylthio)phenyl]-2-oxo-pyridine-3-carbonitrile
• Synonyms: 1,2-dihydro-6-(4-fluorophenyl)-5-[4-(methylthio)phenyl]-2-oxo-pyridine-3-carbonitrile
• CAS NO: 181811-68-7
• Molecular Weight: 336.389
• Mol File: 181811-68-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,2-dihydro-6-(4-fluorophenyl)-5-[4-(methylthio)phenyl]-2-oxo-pyridine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dihydro-6-(4-fluorophenyl)-5-[4-(methylthio)phenyl]-2-oxo-pyridine-3-carbonitrile(181811-68-7)
• EPA Substance Registry System: 1,2-dihydro-6-(4-fluorophenyl)-5-[4-(methylthio)phenyl]-2-oxo-pyridine-3-carbonitrile(181811-68-7)

Safety Data

• Hazardous Substances Data: 181811-68-7(Hazardous Substances Data)

Upstream product

• 10049-21-5 sodium dihydrogenphosphate 
• 107-91-5 cyanoacetic acid amide 

Downstream Products

• 181811-72-3 2-chloro-6-(4-fluorophenyl)-5-[4-(methylthio)phenyl]-pyridine-3-carbonitrile 
• 181811-69-8 1,2-dihydro-6-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]-2-oxo-pyridine-3-carbonitrile 
• 181809-74-5 2-chloro-6-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]pyridine-3-carbonitrile 

Relevant articles and documents

2,3-substituted pyridines for the treatment of inflammation

A class of substituted pyridyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II wherein R1 is selected from hydrido, halo, alkoxy, haloalkoxy, aryl, alkylthio, alkylamino, aralkoxy, azido and alkenyloxy; wherein R2 is selected from hydrido, cyano, hydroxyalkyl, haloalkyl, aminoalkyl, alkylaminoalkyl, alkylcarbonyloxyalkyl, aminocarbonyl and alkylcarbonylaminoalkyl; and wherein R5 and R6 are one or more radicals independently selected from halo, alkylsulfonyl, aminosulfonyl, alkoxy and alkylthio; provided one of R5 and R6 is substituted with alkylsulfonyl, aminosulfonyl, or haloalkylsulfonyl; or a pharmaceutically-acceptable salt thereof.