181697-05-2

Basic information

• Product Name: Benzenesulfonamide, 4-(2-oxo-2-phenylethyl)-
• CAS NO: 181697-05-2
• Molecular Formula: C14H13NO3S
• Molecular Weight: 275.328
• Mol File: 181697-05-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-(2-oxo-2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-(2-oxo-2-phenylethyl)-(181697-05-2)
• EPA Substance Registry System: Benzenesulfonamide, 4-(2-oxo-2-phenylethyl)-(181697-05-2)

Safety Data

• Hazardous Substances Data: 181697-05-2(Hazardous Substances Data)

Upstream product

• 451-40-1 phenyl benzyl ketone 
• 185345-56-6 4-(2-oxo-2-phenylethyl)benzenesulfonyl chloride 
• 22958-64-1 4-(carboxy-methyl)-benzene-sulfonamide 
• 395682-94-7 4-aminosulfonylphenylacetyl chloride 
• 71-43-2 benzene 

Downstream Products

• 181696-05-9 [4-[4-(aminosulfonyl)phenyl]-3-phenylisoxazol-5-yl]-3-methylbutan-1-oic acid 
• 181696-07-1 [4-[4-(aminosulfonyl)phenyl]-3-phenylisoxazol-5-yl]butanoic acid 
• 181696-06-0 [[4-[4-(aminosulfonyl)phenyl]-3-phenylisoxazol-5-yl]-methyloxy]acetic acid 
• 181697-14-3 [4-[4-(aminosulfonyl)phenyl]-3-phenyl-isoxazol-5-yl]carboxamide 
• 181696-08-2 4-[5-cyano-3-phenylisoxazol-4-yl]benzenesulfonamide 
• 181697-10-9 [4-[4-[N-[2,5-dimethylpyrrol]sulfonyl]phenyl]-3-phenylisoxazol-5-yl]butan-1-oic acid 
• 181697-08-5 [4-[4-[N-[2,5-dimethylpyrrol]sulfonyl]phenyl]-3-phenylisoxazol-5-yl]-3-methylbutan-1-oic acid 
• 181697-09-6 [4-[4-[N-[2,5-dimethylpyrrol]sulfonyl]phenyl]-3-phenylisoxazol-5-yl]-methyloxyacetic acid 
• 181697-13-2 [4-[4-[N-[2,5-dimethylpyrrol]sulfonyl]phenyl]-3-phenylisoxazol-5-yl]carboxamide 
• 181697-11-0 [4-[4-[N-[2,5-dimethylpyrrol]sulfonyl]phenyl]-3-phenylisoxazol-5-yl]carboxylic acid 
• 181697-12-1 methyl [4-[4-[N-[2,5-dimethylpyrrol]sulfonyl]phenyl]-3-phenylisoxazol-5-yl]carboxylate 
• 181697-07-4 2-[4-[N-[2,5-dimethylpyrrol]-sulfonyl]phenyl]-1-phenyl-ethan-1-one oxime 
• 198470-84-7 parecoxib 

Relevant articles and documents

Method for preparing Parecoxib

The invention relates to a method for preparing Parecoxib, and belongs to the synthesis field of pharmaceutical chemistry. 1,2-diphenyl-ethanone is used as an starting raw material, a reaction is carried out between the starting raw material and chlorosul

Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof

The present invention relates to sulfonyl-containing 2,3-diarylindole, especially to new compounds of general Formula, to a preparation method for their preparation, to pharmaceutical compositions containing said compound, and to the medical use thereof in the treatment of diseases relating to the inhibition of cyclooxygenase-2 (COX-2).

Discovery of 2-phenyl-3-sulfonylphenyl-indole derivatives as a new class of selective COX-2 inhibitors

2-Sulfonylphenyl-3-phenyl-indole derivatives have been reported to be highly potent and selective COX-2 inhibitors previously. In this paper, the regio-isomeric analogues-2-phenyl-3-sulfonylphenyl-indoles were identified as potent and selective COX-2 inhi