181259-90-5

Basic information

• Product Name: α-O,O'-diethyl amino(2-fluorophenyl)methylphosphonate
• Synonyms: α-O,O'-diethyl amino(2-fluorophenyl)methylphosphonate
• CAS NO: 181259-90-5
• Molecular Weight: 261.233
• Mol File: 181259-90-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: α-O,O'-diethyl amino(2-fluorophenyl)methylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: α-O,O'-diethyl amino(2-fluorophenyl)methylphosphonate(181259-90-5)
• EPA Substance Registry System: α-O,O'-diethyl amino(2-fluorophenyl)methylphosphonate(181259-90-5)

Safety Data

• Hazardous Substances Data: 181259-90-5(Hazardous Substances Data)

Upstream product

• 762-04-9 Diethyl phosphonate 
• 446-52-6 2-Fluorobenzaldehyde 
• 445-29-4 o-fluoro-benzoic acid 
• 393-52-2 2-Fluorobenzoyl chloride 
• 141543-25-1 diethyl (2-fluorobenzoyl)phosphonate 

Downstream Products

• 1006720-03-1 (E)-diethyl (2-fluorophenyl)cinnamidomethylphosphonate 
• 1006719-98-7 diethyl (2-fluorophenyl)(2-chlorobenzamido)methylphosphonate 
• 1006719-82-9 diethyl (2-fluorophenyl)(2-fluorobenzamido)methylphosphonate 
• 1038997-44-2 C₁₈H₂₄FN₂O₅PS 
• 1038997-42-0 C₁₇H₂₂FN₂O₅PS 
• 1038997-49-7 C₁₆H₂₁FN₃O₄PS 
• 1038997-58-8 C₂₀H₂₈FN₂O₆PS 
• 1454615-03-2 C₃₂H₄₄FN₂O₄PS 
• 1621069-66-6 O,O′-diethyl (2-fluorophenyl)(2-(1-hydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yloxy)acetamido)methylphosphonate 
• 1621069-79-1 O,O′-diethyl (2-fluorophenyl)(2-(1-hydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yloxy)propanamido)methylphosphonate 
• 1533457-14-5 diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(2-fluorophenyl)methylphosphonate 
• 1396320-35-6 O,O'-diethyl α-(thiazolo[5,4-b]pyridin-2-ylamino)(2-fluorophenyl)methylphosphonate 
• 1257421-78-5 diethyl (2-(4-chlorophenyl)-1,3,4-thiadiazole-5-sulfonamido)(2-fluorophenyl)methylphosphonate 

Relevant articles and documents

Thienopyridine α- amidogen phenmethyl phosphine ester, a process for their preparation and use

The invention, belonging to the field of pharmaceutical chemicals, relates to a Thienopyridine alpha-amino benzylphosphonate, a preparation method and an application thereof. concretely, the invention relates to a compound of formula I, its medicinal salt, racemate, stereoisomer, or solvate, wherein each substituent is defined in the specification. The invention further relates to a pharmaceutical composition of the compound. The compound of the invention can effectively resist platelet aggregation and/or protect vascular endothelial cells.

Novel coumarin-containing aminophosphonatesas antitumor agent: synthesis, cytotoxicity, DNA-Binding and apoptosis evaluation

A series of novel coumarin-containing α-aminophosphonates were synthesized and evaluated for their antitumor activities against Human colorectal (HCT-116), human nasopharyngeal carcinoma (human KB) and human lung adenocarcinoma (MGC-803) cell lines in vit

Coumarin-containing aminophosphonates bridged with chiral side chain: Synthesis and influence of chirality on cytotoxicity and DNA binding

A series of novel coumarin-containing α-Aminophosphonates with two chiral centers were synthesized and a single-crystal structure of compound 8g (8g', (R)-diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(2- bromophenyl)methylphosphonate) was