181115-73-1

Basic information

• Product Name: C₄₀H₅₂O₂₄
• Synonyms: C₄₀H₅₂O₂₄
• CAS NO: 181115-73-1
• Molecular Weight: 916.838
• Mol File: 181115-73-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₀H₅₂O₂₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₀H₅₂O₂₄(181115-73-1)
• EPA Substance Registry System: C₄₀H₅₂O₂₄(181115-73-1)

Safety Data

• Hazardous Substances Data: 181115-73-1(Hazardous Substances Data)

Relevant articles and documents

Carbohydrate-carbohydrate interactions in water with glycophanes as model systems

The synthesis and conformational properties of glycophanes 2 and 3 (cyclodextrin-cyclophane hybrid receptors containing two maltose units linked by (4-hydroxymethyl) benzoic acid spacer) are described. The binding properties in water of these receptors with a series of 4-nitrophenyl glycosides with α- and β-configurations at the anomeric center have been studied using 1H NMR spectroscopy and molecular mechanics calculations. A comparison of these properties with those of glycophane 1 (an α,α-trehalose containing glycophane) and α-cyclodextrin (αCD) using the same glycosides shows the existence of a stabilizing contribution to the free energy of binding in the case of of glycophanes but not in the case of the αCD system. This contribution is due to carbohydrate-carbohydrate interactions between both host and guest lipophilic sugar surfaces. Glycophanes 1, 2, and 3 show similar α/β selectivity on binding the ligands, despite the great flexibility of 3 related to 1 and 2. Parallels are drawn between the thermodynamic behavior of these model systems and that proposed for sugar- protein interactions.