181045-88-5

Basic information

• Product Name: {(2R,3R,4S,5S,6R)-3,5-Bis-benzyloxy-2-[(1R,2R)-3-benzyloxy-1-benzyloxymethyl-2-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-propoxy]-6-benzyloxymethyl-tetrahydro-pyran-4-yloxy}-acetic acid benzyl ester
• CAS NO: 181045-88-5
• Molecular Weight: 1299.56
• Mol File: 181045-88-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(2R,3R,4S,5S,6R)-3,5-Bis-benzyloxy-2-[(1R,2R)-3-benzyloxy-1-benzyloxymethyl-2-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-propoxy]-6-benzyloxymethyl-tetrahydro-pyran-4-yloxy}-acetic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(2R,3R,4S,5S,6R)-3,5-Bis-benzyloxy-2-[(1R,2R)-3-benzyloxy-1-benzyloxymethyl-2-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-propoxy]-6-benzyloxymethyl-tetrahydro-pyran-4-yloxy}-acetic acid benzyl ester(181045-88-5)
• EPA Substance Registry System: {(2R,3R,4S,5S,6R)-3,5-Bis-benzyloxy-2-[(1R,2R)-3-benzyloxy-1-benzyloxymethyl-2-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-propoxy]-6-benzyloxymethyl-tetrahydro-pyran-4-yloxy}-acetic acid benzyl ester(181045-88-5)

Safety Data

• Hazardous Substances Data: 181045-88-5(Hazardous Substances Data)

Upstream product

• 165557-04-0 (2,4,6-tri-O-benzyl-1-deoxy-1-methylsulfanyl-β-D-galactopyranos-3-yl)-acetic acid benzyl ester 
• 181045-86-3 (2R,3R)-1,4-Bis-benzyloxy-3-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-butan-2-ol 
• 165557-05-1 (1-deoxy-1-methylsulfanyl-β-D-galactopyranos-3-yl)-acetic acid tert-butyl ester 
• 107802-80-2 (2S,3R,4R,5S,6R)-3,4,5-Tris-benzyloxy-2-methyl-6-methylsulfanyl-tetrahydro-pyran 

Relevant articles and documents

Mimics of the sialyl Lewis X tetrasaccharide. Replacement of the N- acetylglucosamine sugar with simple C2-symmetric 1,2-diols

Analogues of sialyl Lewis X have been synthesized that feature replacement of the N-acetylglucosamine residue with C2-symmetric diols. The diols used contain different levels of torsional constraint and various functional groups. The cyclohexyl derived compound 27 was equipotent to sLex in vitro (IC50 0.5 mM).