180088-52-2 Usage
Description
4-Methylumbelliferyl2-sulfamino-2-deoxy-a-D-gluc], also known as 4-MU-GlcNAc2S, is a synthetic substrate used in the diagnosis of Sanfilippo disease type A (MPS IIIA). It is a white powder with unique chemical properties that allow it to be used in fluorometric enzyme assays.
Uses
Used in Medical Diagnostics:
4-Methylumbelliferyl2-sulfamino-2-deoxy-a-D-gluc] is used as a substrate for the lysosomal heparin sulphamidase enzyme, which is deficient in Sanfilippo disease type A (MPS IIIA). The fluorometric enzyme assay involving this substrate helps in the diagnosis of the disease by measuring the enzyme activity in patient samples.
Used in Research:
4-Methylumbelliferyl2-sulfamino-2-deoxy-a-D-gluc] is also used in research settings to study the activity and function of lysosomal enzymes, particularly heparin sulphamidase, and to develop potential therapeutic agents for the treatment of Sanfilippo disease type A (MPS IIIA) and other related lysosomal storage disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 180088-52-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,0,8 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 180088-52:
(8*1)+(7*8)+(6*0)+(5*0)+(4*8)+(3*8)+(2*5)+(1*2)=132
132 % 10 = 2
So 180088-52-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H19NO10S/c1-7-4-12(19)26-10-5-8(2-3-9(7)10)25-16-13(17-28(22,23)24)15(21)14(20)11(6-18)27-16/h2-5,11,13-18,20-21H,6H2,1H3,(H,22,23,24)/t11?,13-,14+,15+,16-/m0/s1
