17983-30-1

Basic information

• Product Name: 3-oxocyclohexanecarbonitrile
• Synonyms: 3-oxocyclohexanecarbonitrile
• CAS NO: 17983-30-1
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.15246
• Mol File: 17983-30-1.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-oxocyclohexanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-oxocyclohexanecarbonitrile(17983-30-1)
• EPA Substance Registry System: 3-oxocyclohexanecarbonitrile(17983-30-1)

Safety Data

• Hazardous Substances Data: 17983-30-1(Hazardous Substances Data)

Usage

General Description

3-oxocyclohexanecarbonitrile, also known as 2-cyanocyclohexanone, is a chemical compound with the molecular formula C7H7NO. It is a colorless liquid that is soluble in organic solvents and is commonly used as a building block in organic synthesis. 3-oxocyclohexanecarbonitrile is often utilized in the production of pharmaceuticals, agrochemicals, and other fine chemicals due to its versatile reactivity and ability to participate in various chemical reactions. It can also be found as an intermediate in the synthesis of other complex organic compounds, making it a valuable tool in the field of organic chemistry. Due to its potential for hazards and health risks, proper handling and safety precautions should be observed when working with 3-oxocyclohexanecarbonitrile.

Upstream product

• 930-68-7 cyclohexenone 
• 7677-24-9 trimethylsilyl cyanide 
• 19158-51-1 P-toluenesulfonyl cyanide 
• 108-94-1 cyclohexanone 
• 100-45-8 3-cyclohexene-1-carbonitrile 
• 90735-45-8 3,3-Dihydroxy-cyclohexanecarbonitrile 
• 74-90-8 hydrogen cyanide 
• 151-50-8 potassium cyanide 

Downstream Products

• 16205-98-4 3-oxo-cyclohexanecarboxylic acid 
• 97087-59-7 α-(3-aminocyclohexyl)methylamine 
• 13338-82-4 1-amino-4-(aminomethyl)cyclohexane 
• 1227808-14-1 C₇H₉F₂N 
• 123762-08-3 3-oxocyclohexanecarboxylic acid benzyl ester 
• 90865-33-1 (R)-3-oxo-cyclohexanecarbonitrile 
• 90865-32-0 (S)-3-oxo-cyclohexanecarbonitrile 
• 21531-46-4 (+)-(S)-3-oxo-1-cylcohexanecarboxylic acid 
• 1206798-46-0 cis-3-aminomethyl-1-cyclohexylamine 
• 1206798-46-0 trans-3-aminomethyl-1-cyclohexylamine 
• 99438-54-7 (R)-pentyl 3-oxocyclohexanecarboxylate 
• 99407-63-3 (+/-)-pentyl 3-oxocyclohexanecarboxylate 

Relevant articles and documents

Preparation of chiral 3-oxocycloalkanecarbonitrile and its derivatives by crystallization-induced diastereomer transformation of ketals with chiral 1,2-diphenylethane-1,2-diol

Chiral 3-oxocycloalkanecarbonitriles were prepared by fractional crystallization and crystallization-induced diastereomer transformation (CIDT) of diastereomeric ketals with (1R,2R)-1,2-diphenylethane-1,2-diol. Investigation of the crystal structures by X

Direct C(sp3)-H Cyanation Enabled by a Highly Active Decatungstate Photocatalyst

A highly efficient, direct C(sp3)-H cyanation was developed under mild photocatalytic conditions. The method enabled the direct cyanation of various C(sp3)-H substrates with excellent functional group tolerance. Notably, complex natural products and bioactive compounds were efficiently cyanated.

Functionalized Polyhydroquinolines from Amino Acids Using a Key One-Pot Cyclization Cascade and Application to the Synthesis of (±)-Δ7-Mesembrenone

Substituted polyhydroquinolines are ubiquitous skeletal cores found in drugs and bioactive natural products. As a new route to access this motif, we successfully developed a one-pot cyclization cascade with high chemocontrol and diastereoselectivity. The sequence generates two cycles, three carbon-carbon bonds, and an all-carbon quaternary center in a highly convergent process. Functionalized polyhydroquinolines and congeners can be accessed from commercially available amino acids. This versatile and robust strategy was applied to the synthesis of (±)-Δ7-mesembrenone.