17973-86-3 Usage
Description
3,6-Dibromopyridazide is a grey-yellow powder that serves as a crucial intermediate in various organic synthesis processes. Its unique chemical structure and properties make it a versatile compound for a range of applications across different industries.
Uses
Used in Pharmaceutical Industry:
3,6-Dibromopyridazide is used as a pharmaceutical intermediate for the development of new drugs and medications. Its chemical properties allow it to be a key component in the synthesis of various pharmaceutical compounds, contributing to the advancement of medical treatments.
Used in Organic Synthesis:
In the field of organic synthesis, 3,6-dibromopyridazide is utilized as a building block for the creation of complex organic molecules. Its reactivity and structural features make it an essential component in the synthesis of a wide array of organic compounds.
Used in Organic Solvents:
3,6-Dibromopyridazide is also employed as a component in the formulation of organic solvents. Its properties enable it to improve the performance and characteristics of solvents used in various applications, including industrial processes and chemical reactions.
Used in Dye Production:
In the dye industry, 3,6-dibromopyridazide is used as a key intermediate for the production of various dyes. Its chemical properties allow it to contribute to the development of dyes with specific color characteristics and performance attributes.
Used in Pesticide Production:
3,6-Dibromopyridazide plays a role in the synthesis of pesticides, where it is used as an intermediate to create effective and targeted pest control agents. Its chemical properties make it a valuable component in the development of new and improved pesticides.
Used in Perfumery:
In the perfumery industry, 3,6-dibromopyridazide is used as an intermediate for the creation of unique and complex fragrances. Its chemical structure allows it to contribute to the development of scents with specific olfactory properties and characteristics.
Preparation
3,6-dibromopyridazine for Synthesis: A mixture of maleic hydrazide (1.1 g, 10 mmol) and PBr5 (4.7 g, 11 mmol) was heated at 100 °C until no more white fumes of hydrogen bromide were produced (~2 h). After cooling, the orange residue was poured into ice water and the resulting mixture was extracted with CH2Cl2 (3 x 20 mL). The organic layer was washed with saturated aqueous NaHCO3, dried over MgSO4, filtered and concentrated. The crude product was purified by flash column chromatography on silica gel (CH2Cl2) to give 3,6-dibromopyridazine as a white solid (1.20 g, 50%).
Check Digit Verification of cas no
The CAS Registry Mumber 17973-86-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,9,7 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 17973-86:
(7*1)+(6*7)+(5*9)+(4*7)+(3*3)+(2*8)+(1*6)=153
153 % 10 = 3
So 17973-86-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H2Br2N2/c5-3-1-2-4(6)8-7-3/h1-2H
17973-86-3Relevant articles and documents
Donor-acceptor-donor-type liquid crystal with a pyridazine core
Yeon, Sil Park,Kim, Dohyung,Lee, Hoosung,Moon, Bongjin
, p. 4699 - 4702 (2006)
(Chemical Equation Presented) A new liquid crystalline material having an ethylenedioxythiophene-pyridazine-ethylenedioxythiophene (EDOT-PDZ-EDOT) core with two peripheral long alkyl chains was prepared. The designated donor-acceptor-donor (D-A-D)-type core structure induced a distinct smectic liquid crystalline phase due to the strong intermolecular interaction. The photophysical property and the layer structure of the liquid crystal were investigated by differential scanning calorimetry, polarized light microscopy, X-ray diffraction, and cyclic voltammetry.
Pyridazine N-Oxides as Photoactivatable Surrogates for Reactive Oxygen Species
Basistyi, Vitalii S.,Frederich, James H.
supporting information, p. 1907 - 1912 (2022/03/27)
A method for the photoinduced evolution of atomic oxygen from pyridazine N-oxides was developed. This underexplored oxygen allotrope mediates arene C-H oxidation within complex, polyfunctional molecules. A water-soluble pyridazine N-oxide was also developed and shown to promote photoinduced DNA cleavage in aqueous solution. Taken together, these studies highlight the utility of pyridazine N-oxides as photoactivatable O(3P) precursors for applications in organic synthesis and chemical biology.
The difference in the CO2adsorption capacities of different functionalized pillar-layered metal-organic frameworks (MOFs)
Gao, Xiang-Jing,Zheng, He-Gen
supporting information, p. 9310 - 9316 (2021/07/12)
The excessive use of fossil energy has caused the CO2concentration in the atmosphere to increase year by year. MOFs are ideal CO2adsorbents that can be used in CO2capture due to their excellent characteristics. Studies of the structure-activity relationship between the small structural differences in MOFs and the CO2adsorption capacities are helpful for the development of efficient MOF-based CO2adsorbents. Therefore, a series of pillar-layered MOFs with similar structural and different functional groups were designed and synthesized. The CO2adsorption tests were carried out at 273 K to explore the relationship between the small structural differences in MOFs caused by different functional groups and the CO2adsorption capacities. Significantly, compound6which contains a pyridazinyl group has a 30.9% increase in CO2adsorption capacity compared to compound1with no functionalized group.
