179162-55-1 Usage
Description
4-(5-(4-(Pentyloxy)phenyl)isoxazol-3-yl)benzoic acid is a chemical compound derived from the optimization of the side chain of the natural product FR901379. It is characterized by its unique structure, which includes a benzoic acid core, an isoxazole ring, and a pentyloxyphenyl group attached to the isoxazole. 4-(5-(4-(pentyloxy)phenyl)isoxazol-3-yl)benzoic acid has potential applications in various fields due to its chemical properties and structural features.
Uses
Used in Pharmaceutical Industry:
4-(5-(4-(Pentyloxy)phenyl)isoxazol-3-yl)benzoic acid is used as a pharmaceutical compound for optimizing the side chain of FR901379, a natural product with potential therapeutic applications. The modification of the side chain aims to enhance the compound's bioactivity, stability, and pharmacokinetic properties, ultimately leading to improved therapeutic efficacy and safety.
Used in Drug Development:
4-(5-(4-(Pentyloxy)phenyl)isoxazol-3-yl)benzoic acid serves as a key intermediate in the development of new drugs based on the natural product FR901379. Its unique structure allows for further chemical modifications and optimization, enabling the design of more effective and targeted therapeutic agents.
Used in Chemical Research:
4-(5-(4-(Pentyloxy)phenyl)isoxazol-3-yl)benzoic acid is utilized in chemical research to study the structure-activity relationships of compounds derived from natural products. By investigating the effects of various modifications to the side chain, researchers can gain insights into the factors that contribute to the biological activity of these compounds and guide the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 179162-55-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,1,6 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 179162-55:
(8*1)+(7*7)+(6*9)+(5*1)+(4*6)+(3*2)+(2*5)+(1*5)=161
161 % 10 = 1
So 179162-55-1 is a valid CAS Registry Number.
179162-55-1Relevant articles and documents
FK463, a novel water-soluble echinocandin lipopeptide: Synthesis and antifungal activity [1]
Tomishima,Ohki,Yamada,Takasugi,Maki,Tawara,Tanaka
, p. 674 - 676 (1999)
-
Preparation method of high-purity micafungin intermediate
-
Paragraph 0028; 0029, (2020/05/30)
The invention belongs to the field of drug synthesis, relates to a preparation method of a high-purity micafungin intermediate, and concretely relates to a preparation method of a micafungin intermediate compound represented by formula A-4. The synthesis method is simple to operate and high in yield, and can meet the requirements of industrial production.
A concise synthesis of isoxazole-based side chain of Micafungin
Rao, Pallavi,Hussain, Ismail,Rao, Venkataramanarao,Sen, Saikat,Oruganti, Srinivas
, p. 2180 - 2187 (2019/06/25)
A concise synthesis of key isoxazole-based side chain of Micafungin, an USFDA approved anti-fungal agent, has been delineated. The route design notably involves a one pot regioselective isoxazole construction from the corresponding aryl aldehyde and alkyne intermediates.
Lipopeptide Compounds and Their Use
-
, (2011/10/04)
The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain lipopeptide compounds comprising a cyclic peptide bearing a lipid side chain (for convenience, collectively referred to herein as “LP compounds”), which, inter alia, are antimicrobial, particularly antibacterial. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to provide an antimicrobial function, particularly an antibacterial function, and in the treatment of diseases and conditions that are mediated by microbes, particularly bacteria, that are ameliorated by the antimicrobial function, particularly an antibacterial function, including bacterial diseases, optionally in combination with another agent, for example, another antibacterial agent.
