179117-29-4

Basic information

• Product Name: chloro-N,N-diethylamino-(3,5-bis(trifluoromethyl)-phenyl)-phosphine
• CAS NO: 179117-29-4
• Molecular Weight: 351.659
• Mol File: 179117-29-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: chloro-N,N-diethylamino-(3,5-bis(trifluoromethyl)-phenyl)-phosphine(CAS DataBase Reference)
• NIST Chemistry Reference: chloro-N,N-diethylamino-(3,5-bis(trifluoromethyl)-phenyl)-phosphine(179117-29-4)
• EPA Substance Registry System: chloro-N,N-diethylamino-(3,5-bis(trifluoromethyl)-phenyl)-phosphine(179117-29-4)

Safety Data

• Hazardous Substances Data: 179117-29-4(Hazardous Substances Data)

Upstream product

• 1069-08-5 diethylphosphoramidous dichloride 
• 328-70-1 3,6-bis(trifluoromethyl)bromobenzene 

Relevant articles and documents

Preparation of chiral phosphorus, sulfur and selenium containing 2-aryloxazolines

A series of enantiomerically pure 2-[2-(diarylphosphino)aryl]-oxazolines was prepared from commercially available or synthetic amino alcohols. For oxazoline formation three procedures were employed: (i) one pot condensation with a 2-halobenzoic acid (ii) ZnCl2 catalyzed condensation with a 2-halobenzonitrile, and (iii) a three step sequence via a 2-halobenzamide and a tosylate or chloride. Phosphinooxazolines containing stereogenic phosphorous were prepared by either diastereoselective nucleophilic substitution of halogenide of Ar1Ar2PCl or by nucleophilic aromatic substitution with LiPAr1Ar2. In addition, sulfur and selenium analogs were prepared.