178454-14-3

Basic information

• Product Name: (2S,3S)-2-Hydroxy-3-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-succinic acid dimethyl ester
• CAS NO: 178454-14-3
• Molecular Weight: 594.659
• Mol File: 178454-14-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S)-2-Hydroxy-3-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-succinic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-2-Hydroxy-3-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-succinic acid dimethyl ester(178454-14-3)
• EPA Substance Registry System: (2S,3S)-2-Hydroxy-3-((2S,3S,4R,5R,6S)-3,4,5-tris-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-succinic acid dimethyl ester(178454-14-3)

Safety Data

• Hazardous Substances Data: 178454-14-3(Hazardous Substances Data)

Upstream product

• 13171-64-7 Dimethyl D-tartrate 
• 107802-80-2 (2S,3R,4R,5S,6R)-3,4,5-Tris-benzyloxy-2-methyl-6-methylsulfanyl-tetrahydro-pyran 

Relevant articles and documents

Mimics of the sialyl Lewis X tetrasaccharide. Replacement of the N- acetylglucosamine sugar with simple C2-symmetric 1,2-diols

Analogues of sialyl Lewis X have been synthesized that feature replacement of the N-acetylglucosamine residue with C2-symmetric diols. The diols used contain different levels of torsional constraint and various functional groups. The cyclohexyl derived compound 27 was equipotent to sLex in vitro (IC50 0.5 mM).