177767-31-6

Basic information

• Product Name: (3(2R,4R)4S)-3-(2,4-dimethyloctanoyl)-4-benzyl-2-oxazolidinone
• CAS NO: 177767-31-6
• Molecular Weight: 331.455
• Mol File: 177767-31-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3(2R,4R)4S)-3-(2,4-dimethyloctanoyl)-4-benzyl-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (3(2R,4R)4S)-3-(2,4-dimethyloctanoyl)-4-benzyl-2-oxazolidinone(177767-31-6)
• EPA Substance Registry System: (3(2R,4R)4S)-3-(2,4-dimethyloctanoyl)-4-benzyl-2-oxazolidinone(177767-31-6)

Safety Data

• Hazardous Substances Data: 177767-31-6(Hazardous Substances Data)

Upstream product

• 359862-15-0 (2R',4R)-3-(2-methylhexanoyl)-4-benzyl-2-oxazolidinone 
• 66050-98-4 (2R)-methyl-1-hexanol 
• 101711-78-8 (3R)-3-propionyl-4-benzyloxazolidin-2-one 
• 177607-72-6 Trifluoro-methanesulfonic acid (R)-2-methyl-hexyl ester 

Downstream Products

• 141205-31-4 microcolin A 

Relevant articles and documents

Total asymmetric synthesis of the potent immunosuppressive marine natural product microcolin A

The total asymmetric synthesis of the potent immunosuppressive compound microcolin A is reported. The synthesis establishes the absolute stereochemistry of microcolin A as C-36R, C-38R, and C-4S on the basis of the diastereoselective preparation of all four possible diastereomers of the lipid region (fragment A) and diastereoselective synthesis of fragment C starting from natural L-(S)-alanine. The strategy involves a convergent assemblage of three optically pure fragments and is amenable to chemical modifications to examine structural analogs for biological study.