17745-84-5 Usage
Description
N,N'-[azinobis(methylidyne-4,1-phenylene)]bis(acetamide), also known as V-50, is a chemical compound with the molecular formula C18H20N4O2. It is a diazonium salt that decomposes under certain conditions to generate free radicals, which are essential for initiating polymerization reactions. This white to off-white powder has a melting point of around 170-173°C and is sparingly soluble in water. Due to its potential to decompose and release toxic fumes when heated, it should be handled with caution.
Uses
Used in Polymerization Industry:
N,N'-[azinobis(methylidyne-4,1-phenylene)]bis(acetamide) is used as a radical initiator for the production of acrylamide-based polymers. It facilitates the polymerization process by generating free radicals, which are crucial for the formation of polymer chains.
Used in Water Treatment Industry:
N,N'-[azinobis(methylidyne-4,1-phenylene)]bis(acetamide) is used as a coagulant in water treatment processes. Its ability to generate free radicals helps in the aggregation of suspended particles, making it easier to remove impurities from water.
Used in Cosmetics Industry:
N,N'-[azinobis(methylidyne-4,1-phenylene)]bis(acetamide) is used as a polymerization initiator in the production of polymers for cosmetic formulations. These polymers can improve the texture, stability, and performance of cosmetic products.
Used in Pharmaceutical Industry:
N,N'-[azinobis(methylidyne-4,1-phenylene)]bis(acetamide) is used as a polymerization initiator in the synthesis of drug delivery systems. The resulting polymers can be used to encapsulate and release active pharmaceutical ingredients in a controlled manner, improving the efficacy and safety of drug administration.
Used in Electronics Industry:
N,N'-[azinobis(methylidyne-4,1-phenylene)]bis(acetamide) is used as a polymerization initiator in the production of conductive polymers for electronic devices. These polymers can be used in various applications, such as sensors, batteries, and flexible electronics.
Used in Environmental Remediation:
N,N'-[azinobis(methylidyne-4,1-phenylene)]bis(acetamide) is used as a polymerization initiator in the synthesis of polymers for environmental remediation. These polymers can be used to adsorb and remove pollutants from soil and water, contributing to a cleaner environment.
Check Digit Verification of cas no
The CAS Registry Mumber 17745-84-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,7,4 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 17745-84:
(7*1)+(6*7)+(5*7)+(4*4)+(3*5)+(2*8)+(1*4)=135
135 % 10 = 5
So 17745-84-5 is a valid CAS Registry Number.
17745-84-5Relevant articles and documents
Further Insights into the Oxidative Pathway of Thiocarbonyl-Type Antitubercular Prodrugs: Ethionamide, Thioacetazone, and Isoxyl
De Freitas Paulo, Tércio,Duhayon, Carine,De Fran?a Lopes, Luiz Gonzaga,Silva Sousa, Eduardo Henrique,Chauvin, Remi,Bernardes-Génisson, Vania
, p. 1879 - 1889 (2021)
A chemical activation study of the thiocarbonyl-type antitubercular prodrugs, ethionamide (ETH), thioacetazone (TAZ), and isoxyl (ISO), was performed. Biomimetic oxidation of ethionamide using H2O2 (1 equiv) led to ETH-SO as the only stable S-oxide compound, which was found to occur in solution in the preferential form of a sulfine (ETH=S=O vs the sulfenic acid tautomer ETH-S-OH), as previously observed in the crystal state. It was also demonstrated that ETH-SO is capable of reacting with amines, as the putative sulfinic derivative (ETH-SO2H) was supposed to do. Unlike ETH, oxidation of TAZ did not allow observation of the mono-oxygenated species (TAZ-SO), leading directly to the more stable sulfinic acid derivative (TAZ-SO2H), which can then lose a SOxH group after further oxidation or when placed in a basic medium. It was also noticed that the unstable TAZ-SO intermediate can lead to the carbodiimide derivative as another electrophilic species. It is suggested that TAZ-SOH, TAZ-SO2H, and the carbodiimide compound can also react with NH2-containing nucleophilic species, and therefore be involved in toxic effects. Finally, ISO showed a very complex reactivity, here assigned to the coexistence of two mono-oxygenated structures, the sulfine and sulfenic acid tautomers. The mono- and dioxygenated derivatives of ISO are also highly unstable, leading to a panel of multiple metabolites, which are still reactive and likely contribute to the toxicity of this prodrug.