1754-62-7Relevant articles and documents
Photodimerization of hydrophobic guests within a water-soluble nanocapsule
Parthasarathy, Anand,Samanta, Shampa R.,Ramamurthy
, p. 73 - 87 (2013)
Conducting reactions in environmentally benign conditions is one of the major objectives of "green chemistry." In this context, developing ways to conduct reactions in water seems obvious. In this report, we present our results on photodimerization of sel
Corey,Hegedus
, p. 1233 (1969)
Synthesis of α-diazoesters from α-hydrazonoesters: Utilization of α-hydrazonoesters and α-diazoesters for convenient interconversion
Yasui, Eiko,Ishimine, Kanako,Nitanai, Sohta,Hatakeyama, Nanami,Nagumo, Shinji
, (2022/04/07)
We have developed a novel method to synthesize α-diazoesters from α-hydrazonoesters with a catalytic amount of Cu(OAc)2 in acetonitrile. When the reaction was carried out under an argon atmosphere, the reaction stopped halfway, suggesting that this reaction required oxygen to reoxidize the catalyst. Since hydrazonoesters can be obtained by reduction of α-diazoesters with P(n-Bu)3 in diisopropyl ether, these 2 compounds are mutually interconvertible with ease. Whereas α-diazoesters are unstable and unsuitable for storage, hydrazonoesters are more stable, especially crystalline hydrazonoesters. Thus, hydrazonoesters, which are suitable for long-term storage, could be conveniently used as precursors for α-diazoesters.
Visible-Light-Driven Isocyanide Insertion to o-Alkenylanilines: A Route to Isoindolinone Synthesis
Dahiya, Anjali,Das, Bubul,Sahoo, Ashish Kumar,Patel, Bhisma K.
, p. 966 - 973 (2022/02/07)
A visible-light-mediated intermolecular radical insertion of isocyanides to electron-deficient o-alkenylanilines leading to isoindolinone is reported. Deuterium (D2O) and H2O18 labelling experiments suggest H and O incorporation in the product. The formation of an N-centered radical (NCR) via stepwise PT/ET process was confirmed by radical trapping experiments, photoluminescence, cyclic voltammetry and DFT studies. This photo cascade methodology is overall a redox neutral process featuring metal-free condition and broad substrate scope (32 examples). The synthesis of analogue of GABA receptor antagonist shows the practical utility of this method. (Figure presented.).
Pd-Catalyzed desulfitative arylation of olefins by: N -methoxysulfonamide
Ojha, Subhadra,Panda, Niranjan
supporting information, p. 1292 - 1298 (2022/02/19)
A novel Pd-catalyzed protocol for the desulfitative Heck-type reaction of N-methoxy aryl sulfonamides with alkenes was reported. The cross-coupling reaction was performed successfully with a variety of olefins to obtain aryl alkenes. Different substituents on the aromatic ring of N-methoxysulfonamides were also found to be compatible with the reaction conditions. Expectedly, the reaction proceeds through CuCl2-promoted generation of the nitrogen radical and subsequent desulfonylation under thermal conditions to afford the aryl radical for the Pd-catalyzed coupling reaction. N-Methoxysulfonamide was further exploited for the synthesis of symmetrical biaryls in the presence of CuCl2. This journal is