174502-37-5 Usage
Description
3-Amino-3-(3,4-dihydroxyphenyl)propanoic acid, also known as L-dopa, is an organic compound that serves as an important precursor in the biosynthesis of certain natural products. It is characterized by the presence of an amino group, a carboxylic acid group, and a 3,4-dihydroxyphenyl moiety, which contribute to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
3-Amino-3-(3,4-dihydroxyphenyl)propanoic acid is used as a reactant in the regiospecific chlorination of (S)-β-tyrosyl-S-carrier protein catalyzed by SgcC3. This process is crucial for the biosynthesis of enediyne antitumor antibiotic C-1027, a potent chemotherapeutic agent that exhibits significant activity against various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 174502-37-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,5,0 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 174502-37:
(8*1)+(7*7)+(6*4)+(5*5)+(4*0)+(3*2)+(2*3)+(1*7)=125
125 % 10 = 5
So 174502-37-5 is a valid CAS Registry Number.
174502-37-5Relevant articles and documents
Parallel synthesis of homochiral β-amino acids
Davies, Stephen G.,Mulvaney, Andrew W.,Russell, Angela J.,Smith, Andrew D.
, p. 1554 - 1566 (2008/02/09)
The parallel asymmetric synthesis of an array of 30 β-amino acids of high enantiomeric purity using the conjugate addition of homochiral lithium N-benzyl-N-(α-methylbenzyl)amide as the key step is accomplished. The experimental simplicity and highly practical nature of the protocol is demonstrated by the efficient parallel conversion of 15 α,β-unsaturated esters to both enantiomeric series of the corresponding β-amino acids in high overall yields and selectivities with minimal purification involved in each step of the reaction protocol.
