1745-77-3

Basic information

• Product Name: 2-BENZYLQUINOLINE
• Synonyms: 2-BENZYLQUINOLINE
• CAS NO: 1745-77-3
• Molecular Formula: C₁₆H₁₃N
• Molecular Weight: 219.28
• Mol File: 1745-77-3.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 352.5°Cat760mmHg
• Flash Point: 151.3°C
• Appearance: /
• Density: 1.117g/cm³
• Vapor Pressure: 7.79E-05mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-BENZYLQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYLQUINOLINE(1745-77-3)
• EPA Substance Registry System: 2-BENZYLQUINOLINE(1745-77-3)

Safety Data

• Hazardous Substances Data: 1745-77-3(Hazardous Substances Data)

Usage

Description

2-BENZYLQUINOLINE is a chemical compound belonging to the quinoline family, characterized by its colorless to pale yellow oily appearance and a melting point of -19 °C. It is recognized for its diverse industrial applications and potential therapeutic properties, making it a valuable chemical in the fields of chemistry, medicine, and agriculture.

Uses

Used in Pharmaceutical Industry:
2-BENZYLQUINOLINE is used as a building block for the synthesis of pharmaceuticals due to its versatile chemical properties, contributing to the development of new drugs with potential therapeutic applications.
Used in Pesticide Industry:
In the pesticide industry, 2-BENZYLQUINOLINE is utilized as a key component in the creation of various pesticides, leveraging its chemical structure to combat pests and protect crops.
Used in Dye Industry:
2-BENZYLQUINOLINE serves as a precursor in the synthesis of dyes, providing a foundation for the production of colorants used in various applications, including textiles and printing.
Used in Research and Development:
2-BENZYLQUINOLINE is used as a research compound for exploring its potential therapeutic properties, such as its activity as an anti-tumor agent, which could lead to the development of new cancer treatments.
Used in Microbiology:
2-BENZYLQUINOLINE is employed as an antimicrobial agent, inhibiting the growth of harmful microorganisms, and has potential applications in the development of new antibiotics or antifungal agents.

InChI:InChI=1/C16H13N/c1-2-6-13(7-3-1)12-15-11-10-14-8-4-5-9-16(14)17-15/h1-11H,12H2

Upstream product

• 101273-59-0 2-benzyl-quinolin-4-ol 
• 24306-31-8 2-benzyl-quinoline-4-carboxylic acid 
• 694-59-7 pyridine N-oxide 
• 1613-37-2 Quinoline N-oxide 
• 91-22-5 quinoline 
• 103-82-2 phenylacetic acid 
• 612-62-4 2-Chloroquinoline 
• 1589-82-8 phenylmagnesium bromide 
• 108-88-3 toluene 
• 257637-46-0 dimethyl quinolin-2-ylphosphonate 
• 7664-41-7 ammonia 
• 108-90-7 chlorobenzene 
• 116249-83-3 benzyl 2-quinolyl sulfoxide 
• 88062-13-9 2-benzyl 3,4-dihydro quinoline 

Downstream Products

• 1139921-59-7 (R)-2-benzyl-1,2,3,4-tetrahydroquinoline 
• 50610-82-7 1,2,3,4-tetrahydro-2-(phenylmethyl)quinoline 
• 3678-74-8 2-(Diphenylmethyl)quinoline 
• 16576-25-3 2-benzoylquinoline 
• 23974-78-9 2-benzylquinoline 1-oxide 
• 95113-34-1 N-(2-quinolyl)-2-benzylidene-1,2-dihydroquinoline 
• 102181-27-1 (3-[2]quinolyl-3-phenyl-propyl)-dimethyl-amine 

Relevant articles and documents

Polar Effects in Free-Radical Reactions. Selectivity and Reversibility in the Homolytic Benzylation of Protonated Heteroaromatic Bases

The homolytic benzylation of protonated 4-cyanopyridine, quinoline, 2-methyl- and 4-methylquinoline, isoquinoline, and quinoxaline is investigated.The great influence of the polar effect and of the reversibility of the addition of the benzyl radical on the reaction selectivity is discussed.It is put forward the hypothesis that the HSAB principle can be extended to free-radical reactions when the polar effect is the dominant factor.

A Metal- and Azide-free Oxidative Coupling Reaction for the Synthesis of [1,2,3]Triazolo[1,5-a]quinolines and their Application to Construct C?C and C-P Bonds, 2-Cyclopropylquinolines and Imidazo[1,5-a]quinolines

An iodine-promoted one-pot cascade oxidative annulation reaction has been developed for the synthesis of [1,2,3]triazolo[1,5-a]quinolines from methyl azaarenes and N-tosylhydrazines. The reaction has a broad substrate scope and can be easily scaled up to gram-scale. 1,2,3-Triazoles are an important skeletal structure for the construction of C?C and C?P bonds, 2-cyclopropylquinolines and imidazo[1,5-a]quinolines, for which different synthetic applications were explored. (Figure presented.).

Catalytic Selective Metal-Free Cross-Coupling of Heteroaromatic N-Oxides with Organosilanes

A metal-free, regioselective C-H functionalization of heteroaromatic N-oxides has been developed. The method enables the synthesis of various benzylated and alkynylated N-heterocycles in a transition-metal-free manner employing organosilanes as coupling partners. The unanticipated reactivity has been exploited for the synthesis of a number of symmetrical disubstituted acetylenes from ethynyltrimethylsilane via carbon-silicon bond metathesis.