172606-22-3

Basic information

• Product Name: 1,1'-(benzene-1,4-diyldimethylene)-bis(3,5-dimethyl-1H-pyrazole)
• Synonyms: 1,1'-(benzene-1,4-diyldimethylene)-bis(3,5-dimethyl-1H-pyrazole);172606-22-31,1'-(benzene-1,4-diyldimethylene)-bis(3,5-dimethyl-1H-pyrazole)
• CAS NO: 172606-22-3
• Molecular Formula: C₁₈H₂₂N₄
• Molecular Weight: 294.39408
• Mol File: 172606-22-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,1'-(benzene-1,4-diyldimethylene)-bis(3,5-dimethyl-1H-pyrazole)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-(benzene-1,4-diyldimethylene)-bis(3,5-dimethyl-1H-pyrazole)(172606-22-3)
• EPA Substance Registry System: 1,1'-(benzene-1,4-diyldimethylene)-bis(3,5-dimethyl-1H-pyrazole)(172606-22-3)

Safety Data

• Hazardous Substances Data: 172606-22-3(Hazardous Substances Data)

Usage

General Description

1,1'-(benzene-1,4-diyldimethylene)-bis(3,5-dimethyl-1H-pyrazole) is a chemical compound with the molecular formula C22H24N4. It is a bis-pyrazole compound that contains two 3,5-dimethyl-1H-pyrazole groups linked by a benzene-1,4-diyldimethylene bridge. 1,1'-(benzene-1,4-diyldimethylene)-bis(3,5-dimethyl-1H-pyrazole) is commonly used in organic synthesis and chemical research as a building block for the preparation of various organic molecules. Its unique structure and properties make it useful for the development of new pharmaceuticals, agrochemicals, and materials. Additionally, it has potential applications in the field of coordination chemistry and catalysis.

Upstream product

• 67-51-6 3,5-dimethyl-1H-pyrazole 
• 623-25-6 p-Xylylene dichloride 
• 106-42-3 para-xylene 
• 623-24-5 1,4-bis(bromomethyl)benzene 

Downstream Products

• 1202709-81-6 1,1'-(benzene-1,4-diyldimethylene)-bis(3,5-dimethyl-1H-pyrazole-4-carbaldehyde) 

Relevant articles and documents

Three Cationic, Nonporous CuI-Coordination Polymers: Structural Investigation and Vapor Iodine Capture

Three cationic nonporous copper(I) coordination polymers containing bis-pyrazolyl flexible ligands have been prepared and characterized, namely, {[Cu(μ-bdb)1.5](PF6)}n (1), {[Cu(μ-bpb)2](PF6)}n/

Capture of volatile iodine by newly prepared and characterized non-porous [CuI]:N-based coordination polymers

Four new non-porous CuI-coordination polymers [Cu2(μ3-I)2(μ-bpb)]n (1a), [Cu(μ2-I)(μ-bpb)]n (1b), [Cu4(μ2-I)4(μ-bpmb)4]n (2), and [CuI

Synthesis, structural, and biological evaluation of the arene-linked pyrazolyl methane ligands and their d9/d10 metal complexes

A series of the p-bis[(1-pyrazolyl)methyl] benzene ligands (L 1-L6) in the DMSO system were synthesized. In the mean time, by using the ligands as a linker, a new family of transition metal coordination polymers, namely, [Cu2(L1)2Cl 4] (1), [Cu2(L2)2Cl4] (2), [Ag(L2)(NO3)] (3), [Zn2(L 2)2(SCN)4] (4) and [Cd2(L 2)(SCN)4] (5) [L1 = 1,4-bis((1H-pyrazol-1-yl) methyl)benzene; L2 = 1,4-bis(3,5-dimethyl-1H-pyrazol-1-yl)methyl) benzene] have been constructed by the reaction of the p-bis[(1-pyrazolyl)methyl] benzene and corresponding to the transition metal compounds in a mixed solution of CH3OH/C2H5OH at mild temperature condition. All the coordination polymers and p-bis[(1-pyrazolyl)methyl]benzene ligands were characterized by elemental analysis, IR spectroscopy, 1H NMR and 13C NMR, and some of them were characterized by UV spectroscopy, thermogravimetric analysis, X-ray powder and X-ray single-crystal diffraction. Structural analyses reveal that the ligands L3-L5 (L 3 = 1,4-bis((4-iodo-1H-pyrazol-1-yl)methyl)benzene, L4 = 1,4-bis((4-iodo-3,5-dimethyl-1H-pyrazol-1-yl)methyl)benzene, L5 = 1,4-bis((4-nitro-1H-pyrazol-1-yl)methyl)benzene,L6 = 1,4-bis((4-nitro-3,5-dimethyl-1H-pyrazol-1-yl) methyl) benzene) are discrete organic compound molecules and the complexes 1-5 are 1D M-L-M coordination polymers, which are further interlinked via hydrogen bonds resulting in 2D or even 3D supermolecular networks. The luminescent properties of the coordination polymers 3, 4 and 5 were examined by luminescence spectra. The analytic results indicate that different metal complexes with the same ligand have different influence on the characteristic photoluminescence. Furthermore, the cytotoxicity of the ligands L1-L6 and complexes 1-5 were evaluated against hepG2 cells. For the ligands of L1-L6, the different substituents of the pyrazole ring slightly influenced the cytotoxicity of the cell. It is found that nitro-compounds have shown the highest cytotoxicity under the same concentration condition. The cytotoxic activity of the complexes 1-5 are strongly increased by the introduction of the transition metals.