17190-77-1 Usage
Description
2,2-dimethyl-1H-indene-1,3(2H)-dione, commonly known as isatin, is an organic compound characterized by its chemical formula C10H9NO2. It is an indole derivative featuring two methyl groups attached to the carbon atoms at the 2 and 3 positions. Isatin presents as a yellowish crystalline solid with a distinct odor and is recognized for its diverse applications in the chemical and pharmaceutical industries, including its use as a precursor in the synthesis of pharmaceuticals, dyes, and agrochemicals. Additionally, isatin exhibits antibacterial, antiviral, and antifungal properties, and its potential medicinal applications are under investigation.
Uses
Used in Pharmaceutical Industry:
Isatin is utilized as a key precursor in the synthesis of various pharmaceuticals due to its ability to form a wide range of biologically active compounds. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Dye Industry:
Isatin serves as a starting material for the production of dyes, capitalizing on its chemical properties to create a variety of colorants used in different applications.
Used in Agrochemical Industry:
Isatin is employed in the agrochemical sector as a precursor for the synthesis of various agrochemicals, contributing to the development of products that enhance crop protection and yield.
Used in Organic Synthesis:
Isatin is a versatile compound in organic synthesis, used to create a multitude of organic compounds for research and commercial purposes, highlighting its importance in the field of chemistry.
Used in Antimicrobial Applications:
Leveraging its antibacterial, antiviral, and antifungal properties, isatin is applied in the development of antimicrobial agents, potentially offering new solutions for combating microbial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 17190-77-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,9 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 17190-77:
(7*1)+(6*7)+(5*1)+(4*9)+(3*0)+(2*7)+(1*7)=111
111 % 10 = 1
So 17190-77-1 is a valid CAS Registry Number.
17190-77-1Relevant articles and documents
Carbopalladation of nitriles: Synthesis of benzocyclic ketones and cyclopentenones via Pd-catalyzed cyclization of ω-(2-iodoaryl)alkanenitriles and related compounds
Pletnev, Alexandre A.,Larock, Richard C.
, p. 9428 - 9438 (2007/10/03)
An efficient procedure for the synthesis of 2,2-disubstituted benzocyclic ketones by intramolecular carbopalladation of nitriles has been developed. The cyclization of substituted 3-(2-iodoaryl)-propanenitriles affords indanones in high yields. The reaction is compatible with a wide variety of functional groups. This methodology has been extended to the synthesis of tetralones and cyclopentenones.
Wittig-Horner reaction of dimethyl phthalide-3-phosphonates with ketones: Synthesis of 3-ylidenephthalides and their conversion to 2,2-disubstituted indan-1,3-diones including spirocyclic compounds
Watanabe,Morimoto,Tomoda,Iwanaga
, p. 1083 - 1086 (2007/10/02)
The Wittig-Horner reaction of dimethyl phthalide-3-phosphonates with various ketones was investigated under the conditions: lithium bis(trimethylsilyl)amide (LHMDS) or sodium hydride in tetrahydrofuran, and cesium carbonate in isopropyl alcohol. The sequential treatment of the 3-ylidenephthalides with diisobutylaluminium hydride (DIBAL-H) and pyridinium dichromate (PDC) afforded 2,2-disubstituted indan-1,3-dione derivatives in modest to high overall yields.
