171869-92-4

Basic information

• Product Name: 5-BROMO-4-CHLORO-3-INDOXYL-ALPHA-L-FUCOPYRANOSIDE
• Synonyms: RARECHEM AH BS 0008;X-ALPHA-L-FUC;X-ALPHA-L-FUCOSIDE;5-BROMO-4-CHLORO-3-INDOXYL-ALPHA-L-FUCOPYRANOSIDE;5-Bromo-4-chloro-3-indolyl-alpha-L-fucopyranoside;5-Bromo-4-chloro-3-indolyla-L-fucopyranoside;5-Bromo-4-chloro-1H-indol-3-yl 6-deoxy-alpha-L-galactopyranoside;X-a-L-Fucoside
• CAS NO: 171869-92-4
• Molecular Formula: C14H15BrClNO5
• Molecular Weight: 392.63
• EINECS: 1533716-785-6
• Mol File: 171869-92-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 611℃
• Flash Point: 323℃
• Appearance: /
• Density: 1.796
• CAS DataBase Reference: 5-BROMO-4-CHLORO-3-INDOXYL-ALPHA-L-FUCOPYRANOSIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-4-CHLORO-3-INDOXYL-ALPHA-L-FUCOPYRANOSIDE(171869-92-4)
• EPA Substance Registry System: 5-BROMO-4-CHLORO-3-INDOXYL-ALPHA-L-FUCOPYRANOSIDE(171869-92-4)

Safety Data

• Hazardous Substances Data: 171869-92-4(Hazardous Substances Data)

Usage

Description

5-BROMO-4-CHLORO-3-INDOXYL-ALPHA-L-FUCOPYRANOSIDE, also known as 5-Bromo-4-chloro-3-indolyl α-L-fucopyranoside, is a synthetic compound that serves as a chromogenic substrate. It is characterized by its ability to produce a blue precipitate when used in specific biochemical reactions, making it a valuable tool in various applications.

Uses

Used in Diagnostic Applications:
5-BROMO-4-CHLORO-3-INDOXYL-ALPHA-L-FUCOPYRANOSIDE is used as a chromogenic substrate for α-L-Fucosidase, a key enzyme involved in the metabolism of fucosylated compounds. The production of a blue precipitate upon enzymatic action allows for the detection and quantification of α-L-Fucosidase activity, which can be useful in diagnosing and monitoring certain conditions related to fucosylation processes.
Used in Research and Development:
In the field of research and development, 5-BROMO-4-CHLORO-3-INDOXYL-AL-L-FUCOPYRANOSIDE is employed as a valuable tool for studying the function and regulation of α-L-Fucosidase. 5-BROMO-4-CHLORO-3-INDOXYL-ALPHA-L-FUCOPYRANOSIDE can be used to investigate the enzyme's role in various biological processes, as well as to develop new methods for detecting and quantifying its activity.
Used in Pharmaceutical Industry:
5-BROMO-4-CHLORO-3-INDOXYL-ALPHA-L-FUCOPYRANOSIDE is used as a starting material or intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical properties and reactivity make it a useful building block for the development of new drugs targeting fucosylation-related diseases or conditions.
Used in Quality Control:
In the quality control of pharmaceutical products, 5-BROMO-4-CHLORO-3-INDOXYL-ALPHA-L-FUCOPYRANOSIDE can be used as a reference compound to ensure the accuracy and reliability of α-L-Fucosidase activity assays. This helps to maintain the quality and consistency of diagnostic tests and other applications that rely on the detection of this enzyme.

Upstream product

• 943138-45-2 5-bromo-6-chloro-isatoic anhydride 
• 3030-19-1 2-amino-5-bromo-6-chlorobenzoic acid 
• 7463-35-6 N-(3-chloro-2-methylphenyl)acetamide 
• 87-60-5 3-chloro-2-methylbenzenamine 
• 125328-77-0 N-acetyl-5-bromo-6-chloroanthranilic acid 
• 125328-80-5 N-(4-bromo-3-chloro-2-methylphenyl)acetamide 
• 627531-47-9 4-amino-2-chloro-3-methylbromobenzene 
• 1447125-37-2 (N-acetyl-5-bromo-4-chloro-indol-3-yl)-2,3,4-tri-O-acetyl-β-L-fucopyranoside 
• 1447125-31-6 (5-bromo-4-chloro-indox-3-ylic acid allyl ester)-2,3,4-tri-O-acetyl-β-L-fucopyranoside 
• 1447125-28-1 5-bromo-4-chloroindoxylic acid allyl ester 
• 1447125-25-8 C₁₅H₁₅BrClNO₄ 
• 1447125-22-5 C₁₃H₉BrClNO₅ 

Relevant articles and documents

Novel efficient routes to indoxyl glycosides for monitoring glycosidase activities

A new efficient synthesis for broad access to indoxyl glycosides was developed. Indoxylic acid allyl ester linked to a sugar structure served as the key intermediate in this route. Selective ester cleavage and mild decarboxylation led to the corresponding indoxyl glycosides in good yields. This synthesis was applied for preparation of indoxyl glycosides of fucose, sialic acid, and 6′-sialyl lactose.