171820-74-9

Basic information

• Product Name: BOC-ORN(ALOC)-OH
• Synonyms: BOC-L-ORN(ALLOC)-OH;BOC-N-DELTA-ALLYLOXYCARBONYL-L-ORNITHINE;BOC-ORN(ALLOC)-OH;BOC-ORN(ALOC)-OH;ALLOC-L-ORN(BOC)-OH DCHA;ALLYLOXYCARBONYL-N-DELTA-BOC-L-ORNITHINE DICYCLOHEXYL AMMONIUM SALT;ALOC-ORN(BOC)-OH DCHA;ALOC-ORNITHINE(BOC)-OH DCHA
• CAS NO: 171820-74-9
• Molecular Formula: C₁₄H₂₄N₂O₆
• Molecular Weight: 316.35
• Mol File: 171820-74-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 504.9 °C at 760 mmHg
• Flash Point: 259.1 °C
• Appearance: /
• Density: 1.153
• Vapor Pressure: 1.46E-11mmHg at 25°C
• Refractive Index: 1.486
• Storage Temp.: -15°C
• PKA: 3.96±0.21(Predicted)
• CAS DataBase Reference: BOC-ORN(ALOC)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-ORN(ALOC)-OH(171820-74-9)
• EPA Substance Registry System: BOC-ORN(ALOC)-OH(171820-74-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 171820-74-9(Hazardous Substances Data)

Usage

Chemical Properties

white powder

InChI:InChI=1/C14H24N2O6/c1-5-9-21-12(19)15-8-6-7-10(11(17)18)16-13(20)22-14(2,3)4/h5,10H,1,6-9H2,2-4H3,(H,15,19)(H,16,20)(H,17,18)/t10-/m0/s1

Upstream product

• 2480-93-5 Boc-Orn(Z)-OH 
• 21887-64-9 N₂-(tert-butoxycarbonyl)-L-ornithine 
• 2937-50-0 Allyl chloroformate 

Relevant articles and documents

An Allyl Protection and Improved Purification Strategy Enables the Synthesis of Functionalized Phosphonamidate Peptides

For modern biophysical methods such as isothermal titration calorimetry, high purity of the inhibitor of interest is indispensable. Herein, we describe a procedure for the synthesis and purification of functionalized phosphonamidate peptides that is able to generate inhibitors for the metalloprotease thermolysin for use in biophysical experiments. The method utilizes an allyl ester/alloc protection strategy and takes advantage of a fast and effective solid-phase extraction (SPE) purification step. Applying this strategy, we were able to synthesize a series of highly polar inhibitors featuring amino- and hydroxy-functionalized side chains in excellent purity.