16642-93-6 Usage
Description
3-Cyanocinnamic acid, also known as mandelonitrile, is an organic compound with the chemical formula C10H7NO. It is a derivative of cinnamic acid, featuring a nitrile group (C≡N) at the 3rd position. 3-Cyanocinnamic acid is a colorless to pale yellow crystalline solid and is known for its various applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
3-Cyanocinnamic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. It serves as a building block for the development of new drugs with potential therapeutic applications.
Used in Antifungal Applications:
3-Cyanocinnamic acid is used as a starting material for the synthesis of triazoles, which exhibit antifungal activities. These synthesized compounds can be employed in the development of antifungal medications to treat various fungal infections.
Used in Dopamine Receptor Antagonist Applications:
3-Cyanocinnamic acid is used as a precursor in the preparation of aminocyclohexylethyl-substituted methylsulfonyloxy and methylsulfonyl tetrahydrobenzazepines. These compounds act as dopamine receptor antagonists and have potential applications in the treatment of psychiatric disorders, such as schizophrenia and other antipsychotic treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 16642-93-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,6,4 and 2 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16642-93:
(7*1)+(6*6)+(5*6)+(4*4)+(3*2)+(2*9)+(1*3)=116
116 % 10 = 6
So 16642-93-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H7NO2/c11-7-9-3-1-2-8(6-9)4-5-10(12)13/h1-6H,(H,12,13)/b5-4+
16642-93-6Relevant articles and documents
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Wiley,Smith
, p. 1560 (1948)
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Iodine-Catalyzed Facile Approach to Sulfones Employing TosMIC as a Sulfonylating Agent
Kadari, Lingaswamy,Palakodety, Radha Krishna,Yallapragada, Lakshmi Prapurna
supporting information, p. 2580 - 2583 (2017/05/24)
A novel iodine-catalyzed functionalization of a variety of olefins and alkynes and direct decarboxylative functionalization of cinnamic and propiolic acids with TosMIC to provide access to various vinyl, allyl, and β-iodo vinylsulfones is described. This simple, efficient, and environmentally benign approach employing inexpensive molecular iodine as a catalyst demonstrates a versatile protocol for the synthesis of highly valuable sulfones, rendering it attractive to both synthetic and medicinal chemistry.
Cinnamamide compounds as metabotropic glutamate receptor antagonists
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Page/Page column 26, (2010/11/26)
The invention relates to compounds of formula I or pharmaceutically acceptable salts or solvates thereof: where R1, R2, R3, A, X, and n are defined in the description. The invention also includes pharmaceutical composition
