165950-84-5 Usage
General Description
(S)-5,6,7,8-Tetrahydro-6-(propylamino)-1-naphthalenol hydrobromide, also known as propylamino-tetralin (PAT), is a chemical compound that belongs to the class of naphthalenol derivatives. It is commonly used as a research tool in neuroscience, specifically in the study of serotonin receptors and their effects on behavior and physiology. PAT acts as a selective serotonin 5-HT1A receptor agonist, meaning it binds to and activates these receptors in the brain, leading to changes in serotonin signaling and neurotransmission. It has been studied for its potential therapeutic applications in the treatment of anxiety, depression, and other mood disorders. PAT is typically administered in a salt form, such as the hydrobromide salt, for improved solubility and bioavailability in research applications.
Check Digit Verification of cas no
The CAS Registry Mumber 165950-84-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,5,9,5 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 165950-84:
(8*1)+(7*6)+(6*5)+(5*9)+(4*5)+(3*0)+(2*8)+(1*4)=165
165 % 10 = 5
So 165950-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H19NO.BrH/c1-2-8-14-11-6-7-12-10(9-11)4-3-5-13(12)15;/h3-5,11,14-15H,2,6-9H2,1H3;1H/t11-;/m0./s1
165950-84-5Relevant articles and documents
IMPROVED PROCESS FOR THE PREPARATION OF CRYSTALLINE FORM II OF ROTIGOTINE
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Page/Page column 3, (2015/12/24)
The present invention relates to an improved, environment friendly and cost effective process for the preparation of crystalline Form II of Rotigotine. Rotigotine, i.e. (6S)-6-{propyl[2-(2-thienyl) ethyl]amino}-5,6,7,8-tetrahydro-l-naphthalenol represented by structural formula (I), is used for the treatment of Parkinson's disease and Willis-Ekbom disease.
Novel Process for the Preparation of Nitrogen Substituted Aminotetralins Derivatives
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Paragraph 0252-0253, (2013/05/08)
The present invention provides an alternative synthesis of N-substituted aminotetralines comprising resolution of N-substituted aminotetralins of formula (II), wherein R1, R2 and R3 are as defined for compound of formula (I).
NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES
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Page/Page column 36, (2012/01/13)
The present invention provides an alternative synthesis of N-substituted aminotetralines comprising resolution of N-substituted aminotetralins of formula (II), wherein R1, R2 and R3 are as defined for compound of formula (I).