1651214-74-2 Usage
Description
tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate is a complex organic compound with a unique molecular structure. It is characterized by a tert-butyl group, a piperazine-1-carboxylate moiety, and a pyridin-3-yl group connected to a pyrido[2,3-d]pyrimidin-2-yl core with various substituents. tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate has potential applications in various fields due to its specific chemical properties and interactions.
Uses
Used in Pharmaceutical Industry:
tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate is used as a precursor in the synthesis of pharmaceutical compounds. Its unique structure allows it to be a key intermediate in the production of drugs targeting specific biological pathways.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, this compound serves as a valuable research tool. It can be used to study the interactions between various molecular targets and potential drug candidates, aiding in the development of new therapeutic agents.
Used in Drug Design and Development:
Due to its specific structural features, tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate can be employed in drug design and development processes. It may contribute to the creation of novel drugs with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 1651214-74-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,5,1,2,1 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1651214-74:
(9*1)+(8*6)+(7*5)+(6*1)+(5*2)+(4*1)+(3*4)+(2*7)+(1*4)=142
142 % 10 = 2
So 1651214-74-2 is a valid CAS Registry Number.
1651214-74-2Relevant articles and documents
Preparation method of palbociclib
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, (2021/06/09)
The invention provides a preparation method of palbociclib. Specifically, ethyl acetoacetate and acetaldehyde are subjected to condensation hydrolysis to prepare 2-acetyl-2-butenoic acid instead of crotonic acid, and tedious steps such as acetyl group loading are not needed, so a synthesis route is simplified. The preparation method is simple and safe, product purity is high, and product yield is improved.
Palbociclib preparation method
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, (2019/04/17)
The invention discloses a palbociclib preparation method, and relates to the field of organic synthesis. The method includes taking a compound I as a starting material; and preforming a five-step reaction to obtain palbociclib. The method has the advantages of simple operation, low requirement on equipment, easily-available raw materials, mild reaction conditions and high yield, so that the methodis suitable for industrial production.
Novel synthetic method of Palbociclib
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, (2017/08/22)
The invention provides a novel synthetic method of Palbociclib, comprising the following steps: 1) under the action of alkali and a solvent, an intermediate V and an intermediate B1 undergo a condensation reaction to obtain a compound VI; 2) the compound VI undergoes exchange with a Grignard reagent, and then the exchange reaction product reacts with an acylation reagent to obtain a compound VII; when X is acetyl, the compound VI is the compound VII; 3) the compound VII undergoes deprotection reaction under the action of hydroxyethanesulphonic acid and finally salification is conducted so as to obtain the finished product Palbociclib X. the synthetic method has a simple process route, is low-cost, and is suitable for industrial production. The synthetic route is as shown in the specification.