1644447-20-0 Usage
General Description
6-cyclopropyl-2-methylnicotinonitrile is a chemical compound with the molecular formula C11H10N2. It is a derivative of nicotinonitrile and is known for its potential applications in pharmaceuticals and agrochemicals. The compound is a yellow to brown crystalline solid that is soluble in organic solvents. It is used as a building block in the synthesis of various biologically active molecules, and its unique structure provides opportunities for the development of new drugs and pesticides. 6-cyclopropyl-2-methylnicotinonitrile is also used as a research tool in the study of biological processes and disease mechanisms, making it an important compound in the field of chemical and pharmaceutical sciences.
Check Digit Verification of cas no
The CAS Registry Mumber 1644447-20-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,4,4,4,4 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1644447-20:
(9*1)+(8*6)+(7*4)+(6*4)+(5*4)+(4*4)+(3*7)+(2*2)+(1*0)=170
170 % 10 = 0
So 1644447-20-0 is a valid CAS Registry Number.
1644447-20-0Relevant articles and documents
Design, synthesis and evaluation of novel 5-phenylpyridin-2(1H)-one derivatives as potent reversible Bruton's tyrosine kinase inhibitors
Zhao, Xinge,Xin, Minhang,Huang, Wei,Ren, Yanliang,Jin, Qiu,Tang, Feng,Jiang, Hailong,Wang, Yazhou,Yang, Jie,Mo, Shifu,Xiang, Hua
, p. 348 - 364 (2015/02/05)
A series of novel reversible Btk inhibitors has been designed based on the structure of the recently reported preclinical drug RN486. The synthesis and SAR of these compounds are described. Among these derivatives, compound 16b was identified to be a potent and orally available reversible agent with satisfactory Btk enzymatic and cellular inhibition in vitro, as well as favorable PK properties and inhibition of arthritis in vivo.
