1642597-27-0

Basic information

• Product Name: 3,5-bis(2-methoxyphenyl)-1H-1,2,4-triazole
• Synonyms: 3,5-bis(2-methoxyphenyl)-1H-1,2,4-triazole
• CAS NO: 1642597-27-0
• Molecular Weight: 281.314
• Mol File: 1642597-27-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5-bis(2-methoxyphenyl)-1H-1,2,4-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-bis(2-methoxyphenyl)-1H-1,2,4-triazole(1642597-27-0)
• EPA Substance Registry System: 3,5-bis(2-methoxyphenyl)-1H-1,2,4-triazole(1642597-27-0)

Safety Data

• Hazardous Substances Data: 1642597-27-0(Hazardous Substances Data)

Upstream product

• 5720-06-9 2-Methoxyphenylboronic acid 
• 106724-85-0 1-benzyl-3,5-dibromo-1H-[1,2,4]triazole 

Downstream Products

• 1642597-21-4 methyl 4-(3,5-bis(2-methoxyphenyl)-1H-1,2,4-triazol-1-yl)benzoate 
• 201530-41-8 deferasirox 

Relevant articles and documents

Microemulsion technique for the novel synthesis of deferasirox using metal mediated coupling

A novel and efficient synthesis of Deferasirox has been accomplished using transition metal catalyzed sequential cross coupling reactions. First stage of the synthesis employs the use of Chan-Lam coupling between 3,5-dibromo-1H[1,2,4] triazole and (4-(methoxycarbonyl)-phenyl)boronic acid to give methyl 4-(3,5-dibromo-1H-1,2,4-triazol-1-yl)benzoate which is further elaboarated to Deferasirox by Suzuki-Miyaura coupling with 2-hydroxyphenyl-boronic acid pinacol ester in microemlusion.