163759-51-1Relevant articles and documents
Antisense modulation of polo-like kinase expression
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Page/Page column 19, (2008/06/13)
Antisense compounds, compositions and methods are provided for modulating the expression of polo-like kinase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding polo-like kinase. Methods of using these compounds for modulation of polo-like kinase expression and for treatment of diseases associated with expression of polo-like kinase are provided.
Nucleosidic phosphoramidite synthesis via phosphitylation: Activator selection and process development
Xie, Chaoyu,Staszak, Michael A.,Quatroche, John T.,Sturgill, Christa D.,Khau, Vien V.,Martinelli, Michael J.
, p. 730 - 737 (2012/12/26)
Nucleosidic phosphoramidites are key building blocks for the automated, solid supported syntheses of oligonucleotide-based drugs. A safe, industrially viable process for preparing nucleosidic phosphoramidites 5-Me-MOE-U and MOE-A has been developed and ut
Antisense modulation of perilipin expression
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Page/Page column 19, (2008/06/13)
Antisense compounds, compositions and methods are provided for modulating the expression of perilipin. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding perilipin. Methods of using these compounds for modulation of perilipin expression and for treatment of diseases associated with expression of perilipin are provided.