16274-34-3Relevant articles and documents
Benzannulation for the regiodefined synthesis of 2-alkyl/aryl-1-naphthols: Total synthesis of arnottin i
Mal, Dipakranjan,Jana, Amit Kumar,Mitra, Prithiba,Ghosh, Ketaki
experimental part, p. 3392 - 3398 (2011/06/22)
The annulation of phthalides with α-alkyl/arylacrylates in the presence of LDA/LHMDS is shown to directly give alkyl/aryl-1-naphthols. The method involving a novel dealkoxycarbonylation obviates the regiochemical issues in the synthesis of polysubstituted naphthalenes, and it forms the key step in a three-step total synthesis of arnottin I, a naphthobenzopyranone natural product.
Bismuth triflate catalyzed [1,3] rearrangement of aryl 3-methylbut-2-enyl ethers
Ollevier, Thierry,Mwene-Mbeja, Topwe M.
, p. 3963 - 3966 (2008/03/11)
An efficient bismuth triflate catalyzed [1,3] rearrangement of aryl 3-methylbut-2-enyl ethers has been developed. The reaction proceeds rapidly and affords the corresponding para- and ortho-prenylated phenols and naphthols in moderate to good yields (up t
Synthesis and vasorelaxant activity of 4-(cyclic amido)-2H-naphtho[1,2-b]pyrans
Chiou, Wen-Fei,Li, Shyh-Yuan,Ho, Li-Kang,Hsien, Ming-Ling,Don, Ming-Jaw
, p. 69 - 75 (2007/10/03)
A series of 4-(cyclic amido)-2H-naphtho[1,2-b]pyrans related to cromakalim (1) has been prepared and their vasorelaxant activities on isolated rat thoracic aorta precontracted with phenylephrine have been evaluated. The relaxant mechanism of 3a was found not through ATP-sensitive K+ channels as cromakalim, but through opening voltage-sensitive K+ channels.